| Bo Zhang,Huibo Shi,Jing Xu,Xiaoqin Li,Mengjun Zeng,Ying Tao,Xing Wu,Jipin Jiang. Adnexal tumor found during a brain-dead donor organ retrieval: a case report. Oncol Transl Med, 2022, 8: 314-317. |
| 脑死亡器官捐献手术中发现附件肿瘤一例 |
| Adnexal tumor found during a brain-dead donor organ retrieval: a case report |
| Received:October 31, 2022 Revised:January 04, 2023 |
| DOI:10.1007/s10330-022-0607-7 |
| 中文关键词: 器官捐献、捐献评估、肿瘤 |
| 英文关键词: organ donation; donation evaluation; tumor |
| 基金项目: |
| Author Name | Affiliation | E-mail | | Bo Zhang | Institute of Organ Transplantation, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology | zhangbo@tjh.tjmu.edu.cn | | Huibo Shi | Organ Procurement Organization (OPO), Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology | | | Jing Xu | Organ Procurement Organization (OPO), Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology | | | Xiaoqin Li | Organ Procurement Organization (OPO), Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology | | | Mengjun Zeng | Organ Procurement Organization (OPO), Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology | | | Ying Tao | Organ Procurement Organization (OPO), Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology | | | Xing Wu | Organ Procurement Organization (OPO), Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology | | | Jipin Jiang* | Organ Procurement Organization (OPO), Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology | 87148236@qq.com |
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| 中文摘要: |
|  背景:器官捐献者捐献前评估至关重要,器官质量直接影响移植术后移植器官和受者近期或远期存活率,同时捐献禁忌症直接关系受者存活乃至医学伦理问题。
病例报道:分析此捐献案例的评估流程。包括:详细病史(原发病和手术史)、血型、传染病、凝血功能、生化功能、肿瘤标准物、结核感染相关指标、微生物培养指标、肺部CT、腹部超声(心脏、肝胆胰脾、肾脏输尿管膀胱、附件等)。 手术中探查:发现腹腔10*10cm占位病变。术中冰冻病理:占位病变为恶性肿瘤。最后捐献和移植手术终止。通过分析此例器官捐献手术中发现附件肿瘤的捐献案例,为后续捐献评估流程提供参考。
结论:本案例提示了术前无创评估的局限性,提示了术前多维度评估器官功能和排除捐献禁忌的必要性。 |
| 英文摘要: |
| Pre-donation evaluation of organ donors is important. Organ quality directly affects both short- and
long-term survival rates of transplanted organs and recipients after transplantation. Contraindications to
donation are directly related to recipient survival and medical ethics. The following information is included
in this organ donation case report: detailed medical history (primary disease and surgical history), blood
type, infectious diseases, coagulation function, biochemical function, tumor biomarker, indicators related to
tuberculosis infection, microbial culture indicators, lung computed tomography (CT) scan, and abdominal
ultrasound (heart, liver, gallbladder, pancreas, spleen, kidneys, ureters, bladder, adnexa). We found a 10
cm × 10 cm space-occupying lesion in the abdominal cavity in this donor organ retrieval surgery. Frozen or
paraffin sections showed that the space-occupying lesion was malignant. The organ donor was not suitable
due to the malignant tumor, and the transplantation surgery was canceled. We analyzed this case of organ
donation to provide a reference for the follow-up donation evaluation process. This case study reveals
the limitations of preoperative non-invasive assessment, the necessity of preoperative multi-dimensional
assessment of organ function, and the exclusion of donation contraindications. |
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