| Shuguo Wang,Haixia Wang,Ping Sui,Bo Han. Gastric signet-ring cell carcinoma with paraneoplastic eosinophilia: A case report and literature review. Oncol Transl Med, 2022, 8: 264-266. |
| 胃印戒细胞癌伴副肿瘤性嗜酸性粒细胞增多症1例报告及文献复习 |
| Gastric signet-ring cell carcinoma with paraneoplastic eosinophilia: A case report and literature review |
| Received:August 04, 2022 Revised:October 13, 2022 |
| DOI：10.1007/s10330-022-0592-2 |
| 中文关键词: 嗜酸性粒细胞增多症，副肿瘤综合征，胃印戒细胞癌 |
| 英文关键词: eosinophilia; paraneoplastic syndrome; gastric signet-ring cell carcinoma |
| 基金项目: |
| Author Name | Affiliation | E-mail | | Shuguo Wang | Qingdao Municipal Hospital | shuguo_wang@163.com | | Haixia Wang | Qingdao Hospital of Traditional Chinese Medicine(Qingdao Hiser hospital) | | | Ping Sui | The Affiliated Yantai Yuhuangding Hospital of Qingdao University | | | Bo Han* | Qingdao Hospital of Traditional Chinese Medicine(Qingdao Hiser hospital) | hbdoctor@126.com |
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| 中文摘要: |
| 我们报告一位40岁的中国女性，患有胃印戒细胞癌，首次诊断为副肿瘤性嗜酸性粒细胞增多症。根治性胃切除术和Billroth II吻合术后24小时内，嗜酸性粒细胞计数急剧下降至正常水平。
患者术后恢复良好，定期随访未发现异常。副肿瘤性嗜酸性粒细胞增多症是一种不寻常的表现，通常无症状，实体恶性肿瘤合并嗜酸性粒细胞核增多症并不常见。据我们所知，这是首次报道的胃癌并发副肿瘤性嗜酸性粒细胞增多症。嗜酸性粒细胞增多症被认为是副肿瘤综合征的表现之一，可以作为恶性疾病的第一临床表现。 |
| 英文摘要: |
| We report the case of a 40-year-old female Chinese patient with gastric signet-ring cell carcinoma that was
first diagnosed because of paraneoplastic eosinophilia. The patient’s eosinophil count reduced markedly to
normal levels within 24 h after radical gastrectomy and Billroth II anastomosis. The patient recovered well
after the surgery and no abnormalities were found during the regular follow-ups. Paraneoplastic eosinophilia
is an unusual manifestation that usually remains asymptomatic; moreover, cases of solid malignant tumors
with eosinophilia are uncommon. To our knowledge, this is the first reported case of paraneoplastic
eosinophilia in a patient with gastric carcinoma. We considered eosinophilia as a manifestation of a
paraneoplastic syndrome, which can be the first clinical manifestation of a malignancy. |
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