| Shuguo Wang,Haixia Wang,Ping Sui,Bo Han. Gastric signet-ring cell carcinoma with paraneoplastic eosinophilia: A case report and literature review. Oncol Transl Med, 2022, 8: 264-266. |
| Gastric signet-ring cell carcinoma with paraneoplastic eosinophilia: A case report and literature review |
| Received:August 04, 2022 Revised:October 13, 2022 |
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| KeyWord:eosinophilia; paraneoplastic syndrome; gastric signet-ring cell carcinoma |
| Author Name | Affiliation | E-mail | | Shuguo Wang | Qingdao Municipal Hospital | shuguo_wang@163.com | | Haixia Wang | Qingdao Hospital of Traditional Chinese Medicine(Qingdao Hiser hospital) | | | Ping Sui | The Affiliated Yantai Yuhuangding Hospital of Qingdao University | | | Bo Han* | Qingdao Hospital of Traditional Chinese Medicine(Qingdao Hiser hospital) | hbdoctor@126.com |
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| Abstract: |
| We report the case of a 40-year-old female Chinese patient with gastric signet-ring cell carcinoma that was
first diagnosed because of paraneoplastic eosinophilia. The patient’s eosinophil count reduced markedly to
normal levels within 24 h after radical gastrectomy and Billroth II anastomosis. The patient recovered well
after the surgery and no abnormalities were found during the regular follow-ups. Paraneoplastic eosinophilia
is an unusual manifestation that usually remains asymptomatic; moreover, cases of solid malignant tumors
with eosinophilia are uncommon. To our knowledge, this is the first reported case of paraneoplastic
eosinophilia in a patient with gastric carcinoma. We considered eosinophilia as a manifestation of a
paraneoplastic syndrome, which can be the first clinical manifestation of a malignancy. |
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