| Jia Shi,Min Gao,Haijun Zhu,Weiwei Lu. One-stage limb Pelnac? reconstruction after removal of skin cancer: safety, efficacy, and aesthetic outcomes. Oncol Transl Med, 2022, 8: 196-200. |
| 皮耐克对皮肤肿瘤切除后的一期肢体重建:安全性、有效性和美学效果分析 |
| One-stage limb Pelnac? reconstruction after removal of skin cancer: safety, efficacy, and aesthetic outcomes |
| Received:May 10, 2022 Revised:August 01, 2022 |
| DOI：10.1007/s10330-022-0574-4 |
| 中文关键词: 皮耐克;肢体重建;皮肤肿瘤 |
| 英文关键词: skin cancer; Pelnac?; large-scale skin reconstruction |
| 基金项目: |
| Author Name | Affiliation | E-mail | | Jia Shi | The Central Hospital of Wuhan, Tongji medical college,Huazhong University of science and Technololy | 1990sj1025@163.com | | Min Gao | The Central Hospital of Wuhan, Tongji medical college,Huazhong University of science and Technololy | | | Haijun Zhu | The Central Hospital of Wuhan, Tongji medical college,Huazhong University of science and Technololy | | | Weiwei Lu* | Tongji Hospital, Tongji Medical Collge, Huazhong University of science and Technololy | 215285906@qq.com |
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| 中文摘要: |
| 目的:评估皮肤肿瘤切除后肢体利用皮耐克一期重建的效果。方法:本前瞻性研究于2017年9月至2020年1月进行，共纳入15例患者。所有患者都行皮肤肿瘤扩大切除和一期大面积皮肤缺损的皮耐克重建。术后定期随访。在6个月的随访中，评估肿瘤复发和疤痕质量(使用温哥华疤痕量表评估)的情况。所有患者无感染、伤口坏死、血肿、血清肿或复发。结果:所有皮肤移植均取得良好效果。其中9例患者的患肢感觉功能正常或接近正常，6例患者患肢存在轻度感觉丧失。但没有明显的功能丧失病例。我们的研究中纳入10名男性和5名女性，平均年龄63.9岁(范围:46-78岁)。平均随访时间20.6个月(范围:12-36个月)。皮肤肿瘤分别发生在足部(4例)、前臂(3例)、腿部(8例)。恶性肿瘤包括恶性黑色素瘤(13.3%)、基底细胞癌(33.3%)、鳞状细胞癌(53.3%)。平均手术时间40.7 min。2名患者接受了放射治疗。平均住院时间为2.6天。平均皮肤缺损面积33.2 cm2(范围:16.6-51.6 cm2)。患者满意度得分(在移植区美观方面)为79.7/100;温哥华疤痕量表得分为3.8。结论:皮耐克材料可有效、可靠地修复皮肤肿瘤术后皮肤缺损。 |
| 英文摘要: |
| Objective To assesse the outcomes of one-stage limb reconstruction after removal of skin cancers defect.
Methods This prospective study was conducted from September 2017 to January 2020 and included
15 patients. All patients underwent extensive tumor resection and one-stage Pelnac? reconstruction of
large skin defects, and regular postoperative follow-up was scheduled. At the 6-month follow-up, tumor
recurrence and scar quality was assessed using the Vancouver Scar Scale (VSS). None of the patients
exhibited infection, wound necrosis, hematoma, seroma, or recurrence.
Results All the skin grafts were well accepted by the patients. Nine patients reported normal or nearnormal
sensory function, while six reported slight sensory loss. No cases of significant functional loss
were observed. We enrolled 10 men and 5 women with a mean age of 63.9 years (range: 46–78 years).
The mean follow-up duration was 20.6 months (range: 12–36 months). The skin tumors were located on
the feet (n = 4), forearms (n = 3), and legs (n = 8). The malignant tumors included malignant melanomas
(13.3%), basal cell carcinomas (33.3%), and squamous cell carcinomas (53.3%). The mean operative time
was 40.7 min. Two patients underwent radiotherapy. The average length of hospital stay was 2.6 days. The
mean skin defect area was 33.2 cm2 (range: 16.6–51.6 cm2). The patient satisfaction score (regarding the
aesthetic appearance of the grafted area) was 79.7/100, and the VSS score was 3.8.
Conclusion Pelnac? dermal templates facilitate efficient and reliable reconstruction of skin defects after
skin cancer resection. |
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