| Yang Yang,Lilin He. Immunotherapy induced hypothyroidism with hyperlipidemia: a case report and literature review. Oncol Transl Med, 2022, 8: 100-103. |
| 免疫治疗相关的甲状腺功能减退合并高脂血症 |
| Immunotherapy induced hypothyroidism with hyperlipidemia: a case report and literature review |
| Received:March 29, 2022 Revised:April 29, 2022 |
| DOI：10.1007/s10330-022-0568-8 |
| 中文关键词: 免疫相关的不良反应，甲状腺功能减退，高脂血症，免疫检查点抑制剂，信迪利单抗，免疫治疗 |
| 英文关键词: immune-related adverse effects (irAEs); hyperlipidemia; hypothyroidism; immune checkpoint; inhibitors (ICIs); sintilimab; immunotherapy |
| 基金项目: |
| Author Name | Affiliation | E-mail | | Yang Yang | First People''''s Hospital of Tianmen,Hubei Tianmen , People’s Republic of China | 867900913@qq.com | | Lilin He* | First People''''s Hospital of Tianmen,Hubei Tianmen , People’s Republic of China | 372135535@qq.com |
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| 中文摘要: |
| 现在免疫检查点抑制剂（ICIs）在临床上的应用越来越广，但在关注免疫治疗疗效的同时也需要警惕免疫相关的不良反应（irAEs）。例如皮肤毒性、胃肠毒性、肝毒性、内分泌毒性、肺毒性。此次我们报道的是一例使用信迪利单抗的过程中出现明显以甘油三酯为主的高脂血症的免疫相关的不良反应。 |
| 英文摘要: |
| In recent years, immune checkpoint inhibitors have been increasingly used in clinical practice. While
considering the efficacy of immunotherapy, it is also necessary to be alert to immune-related adverse
effects (irAEs). These include skin, gastrointestinal, liver, endocrine, and pulmonary toxicities. Here, we
report a case of irAEs of hypothyroidism with marked hyperlipidemia during sintilimab administration. |
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