文章摘要
Dan Wang,Jianhua Wang,Peng Zhu,Shu Zhu,Yi Cheng,Hongchang Luo. Ultrasound-guided No Touch liver pedicle microwave ablation in hepatocellular carcinoma treatment. Oncol Transl Med, 2021, 7: 209-215.
超声引导下No touch肝蒂微波消融损毁术在肝细胞性肝癌治疗中的临床应用研究
Ultrasound-guided No Touch liver pedicle microwave ablation in hepatocellular carcinoma treatment
Received:August 19, 2021  Revised:October 15, 2021
DOI:10.1007/s10330-021-0514-4
中文关键词: 超声引导;肝细胞癌;微波消融;肝蒂
英文关键词: ultrasonic guidance; hepatocellular carcinoma; microwave ablation; liver pedicle
基金项目:程熠 2020年湖北省自然科学基金一般面上项目:KRT18通过调控lncRNA TP53TG1影响宫颈癌发生发展的分子机制研究(2020CFB592)
Author NameAffiliationDepartment
Dan Wang Department of Medical Ultrasound, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China Department of Medical Ultrasound, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China
Jianhua Wang* Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology Department of Oncology
Peng Zhu Hepatic Surgery Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China Hepatic Surgery Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China
Shu Zhu Department of Medical Ultrasound, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China Department of Medical Ultrasound, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China
Yi Cheng Department of Oncology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China Department of Oncology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China
Hongchang Luo and Technology, Wuhan 430030, China Department of Medical Ultrasound, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China
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中文摘要:
  目的 本研究旨在探讨无接触肝蒂微波消融(non - Touch liver pedicle microwave ablation, NTLP-MWA)的可行性、安全性及临床效果。 方法 回顾性分析我院2014年至2015年118例肝癌患者的预后。将患者分为3组。A组35例患者行超声引导下无接触肝蒂微波消融,B组27例患者行常规微波消融,C组56例患者行解剖肝切除术。然后对三组患者术前基础资料、术中资料、术后资料进行分析。 结果 NTLP-MWA组和RMWA组治疗时间、术中出血量、术后肝功能(ALT)与AH组比较差异均有统计学意义(均P < 0.005)。三组患者1年的完全治愈率及局部复发率无明显差异。治疗不是术后早期复发的独立危险因素。三组患者5年总生存率无显著差异。
英文摘要:
    Objective This study aimed to investigate the feasibility, safety, and clinical effect of No Touch liver pedicle microwave ablation (NTLP-MWA). Methods The outcomes of 118 patients diagnosed with hepatocellular carcinoma (HCC) between 2014 and 2015 were retrospectively analyzed. Patients were divided into three groups. In group A, 35 patients underwent ultrasound-guided NTLP-MWA, 27 in Group B were treated with routine microwave ablation (RMWA), and 56 in group C underwent anatomic hepatectomy (AH). The preoperative basic data, intraoperative data, and postoperative data were analyzed among the three groups. Results The treatment time, intraoperative blood loss, and postoperative liver function (alanine transaminase) in the NTLP-MWA and RMWA groups were significantly different from those in the AH group (all P < 0.005). There was no difference in the complete elimination rate and local recurrence within 1 year among the three groups. Treatment was not an independent risk factor for early postoperative recurrence. There was no significant difference in the 5-year overall survival rates among the three groups. Conclusion NTLP-MWA is safe and reliable, in accordance with the principles of oncology treatment, and worth further promotion in clinical practice.
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