| Xiaoli Zou,Changzhi Zhao,Tao Wang,Li Jia,Zhongyi Feng,Xiaoguang Wang,Lei Wei,Xiaobei Liu. The clinical efficacy of percutaneous ethanol-lipiodol injection (PEI) combined with high-intensity focused ultrasound (HIFU) for small hepatocellularcarcinomain special or high-risk locations. Oncol Transl Med, 2021, 7: 172-176. |
| PEI联合HIFU治疗特殊/高危部位小肝癌的临床研究 |
| The clinical efficacy of percutaneous ethanol-lipiodol injection (PEI) combined with high-intensity focused ultrasound (HIFU) for small hepatocellularcarcinomain special or high-risk locations |
| Received:January 08, 2021 Revised:August 10, 2021 |
| DOI：10.1007/s10330-021-0477-7 |
| 中文关键词: 肝癌；特殊部位；HIFU；经皮肝穿刺；无水酒精；碘化油 |
| 英文关键词: hepatocellular carcinoma; special location; high-intensity focused ultrasound (HIFU); percutaneous ethanol-lipiodol injection (PEI); ethanol; lipiodol |
| 基金项目:2016年大连市卫计委科研课题 |
| Author Name | Affiliation | E-mail | | Xiaoli Zou | Department of Ultrasound Imaging, The Affiliated Dalian Municipal Friendship Hospital of Dalian Medical University, Dalian 116001, China | 1324470905@qq.com | | Changzhi Zhao | Department of Hepatobiliary Surgery, The Affiliated Dalian Municipal Friendship Hospital of Dalian Medical University, Dalian 116001, China | | | Tao Wang | Department of Hepatobiliary Surgery, The Affiliated Dalian Municipal Friendship Hospital of Dalian Medical University, Dalian 116001, China | | | Li Jia | Department of Ultrasound Imaging, The Affiliated Dalian Municipal Friendship Hospital of Dalian Medical University, Dalian 116001, China | | | Zhongyi Feng | Department of Hepatobiliary Surgery, The Affiliated Dalian Municipal Friendship Hospital of Dalian Medical University, Dalian 116001, China | | | Xiaoguang Wang | Department of Hepatobiliary Surgery, The Affiliated Dalian Municipal Friendship Hospital of Dalian Medical University, Dalian 116001, China | | | Lei Wei | Department of Hepatobiliary Surgery, The Affiliated Dalian Municipal Friendship Hospital of Dalian Medical University, Dalian 116001, China | | | Xiaobei Liu* | Department of Hepatobiliary Surgery, The Affiliated Dalian Municipal Friendship Hospital of Dalian Medical University, Dalian 116001, China | 13942077177@139.com |
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| 中文摘要: |
| 目的 观察超声引导下瘤內注射无水酒精碘化油混合乳剂（PEI）联合高强度聚焦超声（HIFU）治疗特殊/高危部位小肝癌的近期疗效及并发症。方法 40例特殊/高危部位小肝癌病人随机分两组：20例接受PEI联合HIFU治疗，20例为单纯HIFU治疗，两组病人的平均年龄、肝功能、肿瘤部位、肿瘤数量及大小无显著差异（P＞0.05）。结果 两组病人消融参数比较差异有显著性（P＜0.05），相同功率下，PEI+HIFU组消融率明显大于HIFU组，并发症也明显轻于HIFU组。结论 PEI与HIFU联合应用，对特殊/高危部位小肝癌消融治疗的有效性和安全性有更好的临床应用价值。 |
| 英文摘要: |
| Objective: The objective of this study was to explore the short-term effects and postoperative complications
of ultrasound-guided percutaneous ethanol-lipiodol injection (PEI) combined with high-intensity focused
ultrasound (HIFU) for the treatment of small hepatocellular carcinoma in a special or high-risk location.
Methods: Forty patients with small liver cancer in a special or high-risk location were randomly divided
into two groups: 20 patients were treated with PEI combined with HIFU (P + H group), and 20 patients were
treated with HIFU alone (H group). There were no significant differences in average age, liver function,
tumor location, tumor number, or tumor size between the two groups (P > 0.05).
Results: Significant differences were observed in ablation parameters between the two groups (P < 0.05).
Under the same power, ablation rates of the P + H group were significantly higher than those in the H group,
and postoperative complications in the P + H group were significantly lower than those in the H group (P
< 0.05).
Conclusion: The combination of PEI and HIFU has better clinical value than HIFU alone for small-cell
liver cancer in special or high-risk locations. |
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