| Shixun Wang,Gaoyang Lin,Na Ge,Ronghua Yang,Mengjun Li,Donghua Zhao,Peng Li,Yongjie Wang. Correlation between clinicopathological parameters of lung adenocarcinoma and lymph node metastasis. Oncol Transl Med, 2020, 6: 165-169. |
| 肺腺癌病理亚型与淋巴结转移的相关性研究 |
| Correlation between clinicopathological parameters of lung adenocarcinoma and lymph node metastasis |
| Received:April 19, 2020 Revised:July 24, 2020 |
| DOI：10.1007/s10330-020-0421-1 |
| 中文关键词: 肺腺癌；病理亚型；淋巴结转移；危险因素 |
| 英文关键词: lung adenocarcinoma; lymph node metastasis; pathological subtype; risk factors |
| 基金项目: |
| Author Name | Affiliation | E-mail | | Shixun Wang | Qingdao University, Qingdao 266000, China | qdxwwsx@163.com | | Gaoyang Lin | Department of Thoracic Surgery, The Affiliated Qingdao Hiser Medical Center of Qingdao University, Qingdao 266000, China | | | Na Ge | Department of Thoracic Surgery, The Affiliated Hospital of Qingdao University, Qingdao 266000, China | | | Ronghua Yang | Department of Thoracic Surgery, The Affiliated Hospital of Qingdao University, Qingdao 266000, China | | | Mengjun Li | Qingdao University, Qingdao 266000, China | | | Donghua Zhao | Qingdao University, Qingdao 266000, China | | | Peng Li | Qingdao University, Qingdao 266000, China | | | Yongjie Wang* | Department of Thoracic Surgery, The Affiliated Hospital of Qingdao University, Qingdao 266000, China | wyjtgzy@163.com |
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| 中文摘要: |
| 目的 研究肺腺癌病理亚型与淋巴结转移的相关规律及危险因素。
方法 收集分析258例术后病理为肺腺癌患者，统计纳入研究者的基本信息，采用单因素及多因素分析。
结果 肿瘤最大直径是淋巴结转移的独立危险因素。肺腺癌患者肿瘤最大直径越大，其发生淋巴结转移的可能性就越高。病理亚型为实体型可作为上纵隔及隆突下淋巴结区的独立危险因素，更易发生上纵隔及隆突下淋巴结转移。原发位于肺下叶的腺癌淋巴结转移率可能会高于肺上叶的腺癌。
结论 对于已知肺腺癌患者的病理亚型，可用于预测其各区域淋巴结的转移情况，并用于指导手术淋巴结的清扫以期望改善患者预后。 |
| 英文摘要: |
| Objective The aim of the study was to study the correlation between the clinicopathological parameters
of lung adenocarcinoma and lymph node metastasis and identify the risk factors of lymph node metastasis.
Methods The data of 258 patients with postoperative lung adenocarcinoma (mainly based on their
pathological data) were collected and analyzed, and their basic information was counted.
Results Maximum tumor diameter was found to be an independent risk factor for lymph node metastasis.
The larger the maximum diameter of the tumor in patients with lung adenocarcinoma, the higher the likelihood
of lymph node metastasis. Solid predominant adenocarcinoma with mucin production is as an independent
risk factor for superior mediastinal and subcarinal lymph node metastasis. Primary adenocarcinomas in
the lower lobe of the lung may have a higher rate of lymph node metastasis than those in the upper lobe.
Conclusion The known pathological subtypes of lung adenocarcinoma can be used for the prediction
of lymph node metastasis in various regions and guide the dissection of lymph nodes that would improve
patients’ prognosis. |
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