| Jinkun Guo,ZhongYin Zhou. Proton pump inhibitors and stomach neoplasm. Oncol Transl Med, 2020, 6: 26-29. |
| 质子泵抑制剂与胃肿瘤 |
| Proton pump inhibitors and stomach neoplasm |
| Received:October 15, 2019 Revised:December 30, 2019 |
| DOI：10.1007/s10330-019-0384-4 |
| 中文关键词: 质子泵抑制剂；胃肿瘤；综述 |
| 英文关键词: proton pump inhibitor (PPI); stomach neoplasm; review |
| 基金项目:湖北省公益性项目 (2013BKB013); 湖北省自然科学基金 (2011CHB025) |
|
| Hits: 9226 |
| Download times: 11429 |
| 中文摘要: |
| [摘要]
目的:为探讨质子泵抑制剂与胃肿瘤之间的关系，本文对这一领域的研究进行综述，并试图找出这些联系背后的原因。
方法:我们阅读了关于质子泵抑制剂和胃肿瘤的研究，并根据胃肿瘤的分类，探索质子泵抑制剂与不同类型胃肿瘤之间的关系。
结果:长期使用质子泵抑制剂可导致胃感染、胃泌素水平升高和反弹性酸分泌增多，这些与胃肿瘤的发生有直接或间接的关系。
结论:PPI可增加胃底息肉的发病风险，而PPI可增加胃癌的发病风险尚需要更多的证据来证实。
关键词 质子泵抑制剂；胃肿瘤；综述 |
| 英文摘要: |
| This study aimed to explore the relationship between proton pump inhibitors (PPIs) and gastric tumors
and determine the reasons behind these connections. We reviewed studies on PPIs and stomach tumors.
We explored the relationship between PPIs and different types of gastric neoplasms according to the
classification of gastric neoplasms. Long-term use of PPIs is associated with stomach infection, high gastrin
levels, and rebound acid hypersecretion, which are directly or indirectly related to the development of
gastric neoplasms. PPIs can increase the risk of gastric fundal polyps. Further evidence is needed to prove
that it can increase the risk of gastric cancer. |
|
View Full Text
Download reader HTML全文 |
| Close |