文章摘要
Xiao dan Yang,Tao Han,Yue Zhang,Yanming Zhang,Gao Li,Yongye Liu,Zhaozhe Liu,Zhendong Zheng. The application of 3D printing in the development of RECIST standard for evaluating tumor efficacy. Oncol Transl Med, 2020, 6: 39-42.
3D打印技术在肿瘤疗效评估中的作用(Recist评价标准)
The application of 3D printing in the development of RECIST standard for evaluating tumor efficacy
Received:August 19, 2019  Revised:September 11, 2019
DOI:10.1007/s10330-019-0374-4
中文关键词: 3D打印,Recist评价标准,化疗
英文关键词: Three-dimensional (3D) printing; RECIST standard; chemotherapy
基金项目:
Author NameAffiliationE-mail
Xiao dan Yang General Hospital of Northern Theater Command yxdoctor_88@163.com 
Tao Han General Hospital of Northern Theater Command  
Yue Zhang Jinzhou Medical University  
Yanming Zhang Jinzhou Medical University  
Gao Li Shenyang Pharmaceautical University  
Yongye Liu General Hospital of Northern Theater Command  
Zhaozhe Liu General Hospital of Northern Theater Command  
Zhendong Zheng* General Hospital of Northern Theater Command zhengzhdong@163.com 
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中文摘要:
  三维打印技术作为一种新的技术手段,可以将传统的计算机断层扫描(CT)或磁共振成像(MRI)转换为计算机辅助设计文件,将二维空间结构发展为三维成像结构。近年来,该技术已广泛应用于头颈外科、骨科、生物医学等医学领域。本文通过实例对比3D打印技术,弥补了Recist标准在评估人体肿瘤变化方面存在的诸多问题。Recist评价标准目前被认为是评估化疗和靶向肿瘤治疗前后的变化的标准。这取决于CT对最长直径的靶病灶的确定,并结合患者病情进展、稳定性和缓解程度的变化进行评估。三维打印技术在评估化疗和靶向治疗后人类肿瘤的变化方面更加直观;然而,可用的报告很少。
英文摘要:
    Three-dimensional (3D) printing technology, as a novel technical method, can convert conventional computed tomography (CT) or magnetic resonance imaging (MRI) scans to computer-aided design files and develop a 2D spatial structure into a 3D imaging structure. In recent years, the technology has been widely used in numerous areas, including head and neck surgery, orthopedics, and bio-medicinal research. This article uses examples of 3D printed tumor models to develop Response Evaluation Criteria In Solid Tumors (RECIST) standards to evaluate the changes in tumors. RECIST standard is currently recognized as the standard for assessment of chemotherapy. Under the RECIST standard, changes occurring in tumors before and after the surgery, are evaluated. The assessment depends upon a CT evaluation of the changes in the lesions with the largest diameters. In addition, the disease progression and stability of remission is also assessed. Three-dimensional printing technology is more intuitive in the evaluation of changes to human tumors following chemotherapy and targeted therapy. However, a few reports are available.
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