| Yang Tang,Li Yang,Xianglin Yuan. Treatment of aggressive pancreatic solid pseudo-papillary neoplasms with apatinib plus S-1 chemotherapy: A case report and literature review. Oncol Transl Med, 2018, 4: 219-221. |
| Treatment of aggressive pancreatic solid pseudo-papillary neoplasms with apatinib plus S-1 chemotherapy: A case report and literature review |
| Received:September 14, 2018 Revised:October 18, 2018 |
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| KeyWord:solid pseudopapillary neoplasm; apatinib; S1; chemotherapy |
| Author Name | Affiliation | E-mail | | Yang Tang | Tongji Hospital affiliated with Tongji Medical College, Huazhong University of Science and Technology, Hankou District, Wuhan, Hubei Province, China | tangyangtjmu@126.com | | Li Yang | Tongji Hospital affiliated with Tongji Medical College, Huazhong University of Science and Technology, Hankou District, Wuhan, Hubei Province, China | | | Xianglin Yuan | Tongji Hospital affiliated with Tongji Medical College, Huazhong University of Science and Technology, Hankou District, Wuhan, Hubei Province, China | Xlyuan1020@163.com |
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| Abstract: |
| Solid pseudopapillary neoplasm (SPN) is a rare indolent pancreatic neoplasm that occurs mostly in females.
Although the malignancy potential is quite limited for SPN, these tumors can sometimes be aggressive
and lead to inferior prognosis for male patients. In this case report, we present a special case of a male
patient with SPN who experienced an aggressive tumor expansion after two surgical resections. For further
treatment, we decided to administer chemotherapy with apatinib and S-1, and subsequent CT/MRI tumor
monitoring indicated satisfactory control of tumor expansion. The effectiveness of apatinib plus the S-1
regimen should be tested for more patients with SPN in the future. |
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