| Xiaozhen Zhan,Baiying Liu,Wenbin Li,Taotao Zhang,Xiangwen Zhang,Guo Zu. Small cell carcinoma of the gastric remnant: a case report. Oncol Transl Med, 2018, 4: 76-79. |
| 残胃小细胞癌1例 |
| Small cell carcinoma of the gastric remnant: a case report |
| Received:April 09, 2018 Revised:May 27, 2018 |
| DOI：10.1007/s10330-018-0268-8 |
| 中文关键词: 小细胞癌、胃、胃癌、残胃癌、残胃 |
| 英文关键词: small cell carcinoma (SCC); gastric; stump cancer; gastric remnant; gastric carcinoma |
| 基金项目: |
| Author Name | Affiliation | E-mail | | Xiaozhen Zhan | Department of Gastroenterology, Dalian Municipal Central Hospital, Dalian 116033, China
Dalian Medical University, Dalian 116044, China. | 17605054233@163.com | | Baiying Liu | Department of Gastroenterology, Dalian Municipal Central Hospital, Dalian 116033, China
Dalian Medical University, Dalian 116044, China. | | | Wenbin Li | Department of Gastroenterology, Dalian Municipal Central Hospital, Dalian 116033, China | | | Taotao Zhang | Department of Gastroenterology, Dalian Municipal Central Hospital, Dalian 116033, China | | | Xiangwen Zhang | Department of Gastroenterology, Dalian Municipal Central Hospital, Dalian 116033, China | | | Guo Zu* | Department of Gastroenterology, Dalian Municipal Central Hospital, Dalian 116033, China | zushanghai@163.com |
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| 中文摘要: |
| 目标 小细胞癌主要发生在肺部，发生在残胃中是非常罕见的。在此我们报告1例残胃小细胞癌，以提高对残胃小细胞癌的诊断和治疗。
方法 我们报告一1例71岁残胃小细胞癌男性患者，症状为上腹痛、反酸和嗳气，38年前曾行毕氏二式胃空肠吻合术。
结果 查体未见明显异常。除外贫血化验检查均在正常范围。术后病理示：残胃吻合口处见一隆起型肿物，大小约5.0×5.0×2.5cm，侵及全层。免疫组化示：CK (-), LCA (+), Syn (+), CD56 (+), Ki-67 (+>50%)。
结论 残胃小细胞癌的病理、症状、诊断、治疗和预后均与胃小细胞癌相似。残胃小细胞癌的标准治疗方案尚不明确，但我们建议行手术治疗联合辅助化疗以延长患者生存寿命。我们的病例提示替吉奥胶囊辅助化疗对治疗残胃小细胞癌有效。为了确定残胃小细胞癌的最佳治疗方案，需要进行全面的检查。 |
| 英文摘要: |
| Objective?Small cell carcinoma (SCC) is mostly found in the lungs. It is extremely rare in the gastric remnant. Here, we report a case and review the literature in order to improve the diagnosis and treatment of SCC of the gastric remnant.
Methods?We report a case of SCC of the gastric remnant in a 71-year-old male Chinese patient who presented with epigastric pain, acid regurgitation, and belching and who underwent Billroth II gastrectomy more than 38 years ago.
Results?Physical examination showed no obvious abnormalities. Laboratory data were within normal limits, except for anemia. Pathology of the mass showed a protruded tumor measuring 5.0 × 5.0 × 2.5 cm at the anastomotic edge of the gastric remnant that infiltrated through the full wall of the stomach; this was confirmed by immunohistochemical staining for cytokeratin [CK (-)], leukocyte common antigen (LCA) ( ), synaptophysin ( ), CD56 ( ), and Ki-67 ( > 50%).
Conclusion?SCC of the gastric remnant is extremely rare, although the pathology, symptoms, diagnosis, treatment, and prognosis of SCC are similar to those of gastric SCC. Although the standard treatment of SCC of the gastric remnant remains unclear, effective surgical resection and subsequent multiagent chemotherapy should be performed for long-term survival. Our case shows the efficacy of tegafur-gimeracil-oteracil-potassium capsule chemotherapy. Examination of a large series is required to determine the optimal treatment strategy for SCC of the gastric remnant.
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