| kaihua liu,Hongqiang wang,Lei Yu,Peitao Wang,Zhijun Liu,Lijiang Sun,Hongsheng Yu,Shenqian Li. Primary urachal adenocarcinoma: a rare case report. Oncol Transl Med, 2017, 3: 267-269. |
| 罕见原发性脐尿管腺癌1例报道 |
| Primary urachal adenocarcinoma: a rare case report |
| Received:December 07, 2017 Revised:January 05, 2018 |
| DOI：10.1007/s10330-017-0246-6 |
| 中文关键词: 脐尿管癌；脐尿管；膀胱癌；治疗 |
| 英文关键词: urachal tumor; urachus; bladder cancer; therapy |
| 基金项目: |
| Author Name | Affiliation | E-mail | | kaihua liu | The Medical College of Qingdao University, Qingdao 266071, China | 1099791031@qq.com | | Hongqiang wang | Department of Andrology, The Affiliated Hospital of Qingdao University, Qingdao 266003, China | | | Lei Yu | Department of Andrology, The Affiliated Hospital of Qingdao University, Qingdao 266003, China | | | Peitao Wang | Department of Andrology, The Affiliated Hospital of Qingdao University, Qingdao 266003, China | | | Zhijun Liu | Department of Clinical Laboratory, The Affiliated Hospital of Qingdao University,Qingdao 266003, China | | | Lijiang Sun | Department of Urology, The Affiliated Hospital of Qingdao University, Qingdao 266003, China | | | Hongsheng Yu | Department of Oncology, The Affiliated Hospital of Qingdao University, Qingdao 266003, China | | | Shenqian Li* | The Affiliated Hospital of Qingdao University | lishenqian@126.com |
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| 中文摘要: |
| 原发性脐尿管癌是一种非常罕见的恶性肿瘤。大多数病例中表现为高级别，进展期，通常在就诊时已经发生局部或远处转移,预后很差。在本文中，我们报道一个非常有意义和罕见原发性脐尿管腺癌伴印戒细胞癌的病例，病人男性58岁，主要表现为下腹部的包块和不适。我们成功进行了手术治疗，手术范围包括大部分的膀胱壁、脐尿管肿物和脐部，此外，患者也进行了以5-氟尿嘧啶和顺铂为基础的全身化疗。术后随访一年，未发现复发或转移。因此，我们认为对于局限性脐尿管肿瘤保留膀胱的部分切除术可以使病人有较高的生活质量，结合全身化疗是治疗的主要方法。 |
| 英文摘要: |
| Primary urachal carcinoma is a very rare cancer with a poor prognosis. It generally presents as a highgrade,
high-stage tumor, and in most cases the patient has developed regional or distant metastasis
at the time of presentation. Here, we report a very interesting case of primary urachal adenocarcinoma
with signet ring cell carcinoma in a 58-year-old male who presented with a lower abdominal mass and
discomfort. In this case, urachal carcinoma was successfully treated with surgery using an extended partial
bladder cystectomy approach with excision of the urachal mass and umbilicus. The patient also underwent
systematic chemotherapy with 5-fluorourical and cisplatin. During the 12-month follow-up period, the patient
did not experience recurrence or metastasis. Overall, we found that an organ preserving extended partial
cystectomy along with chemotherapy was an optimal treatment method that helped improve the patient’s
quality of the life with no recurrence of cancer so far. |
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