| Yao Han,Lin Zhen,Baiying Liu,Xiaozhen Zhan,Wenbin Li,Taotao Zhang,Xiangwen Zhang,Guo Zu. Gastric adenocarcinoma with hepatoid adenocarcinoma: A case report and literature review. Oncol Transl Med, 2018, 4: 35-37. |
| Gastric adenocarcinoma with hepatoid adenocarcinoma: A case report and literature review |
| Received:November 22, 2017 Revised:February 16, 2018 |
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| KeyWord:gastric cancer; adenocarcinoma; hepatoid; immunohistochemistry |
| Author Name | Affiliation | E-mail | | Yao Han | Department of Gastroenterology,Dalian Municipal Central Hospital | hanyaomvp1@163.com | | Lin Zhen | Department of Gastroenterology,Dalian Municipal Central Hospital | | | Baiying Liu | Department of Gastroenterology,Dalian Municipal Central Hospital | | | Xiaozhen Zhan | Department of Gastroenterology,Dalian Municipal Central Hospital | | | Wenbin Li | Department of Gastroenterology,Dalian Municipal Central Hospital | | | Taotao Zhang | Department of Gastroenterology,Dalian Municipal Central Hospital | | | Xiangwen Zhang | Department of Gastroenterology,Dalian Municipal Central Hospital | | | Guo Zu | Department of Gastroenterology,Dalian Municipal Central Hospital | zushanghai@163.com |
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| Abstract: |
| Objective Hepatoid adenocarcinoma of the stomach is exceedingly rare. Only a few cases have been
reported worldwide. In this report, we describe our pathological findings along with a review of the literature
to improve our understanding of the disease and prevent misdiagnosis, as well as to provide evidence for
its treatment and prognosis.
Methods A 68-year-old male patient was admitted to our hospital (Dalian Municipal Central Hospital,
Dalian, China) complaining of upper abdominal pain. Physical examination and regular laboratory blood
tests showed no obvious abnormalities. A contrast-enhanced computed tomography scan displayed a 3.0
cm × 3.0 cm mass in the gastric antrum, but no metastasis was found in the adjacent organs.
Results A radical gastrectomy was performed and postoperative histopathology showed a moderately
differentiated adenocarcinoma with partial hepatoid adenocarcinoma.
Conclusion Hepatoid adenocarcinoma of the stomach is a rare malignant neoplasm. The diagnostic
criteria for hepatoid adenocarcinoma of the stomach depends mainly on the clinical, radiographic, and
histopathological findings. Pathomorphology and immunohistochemical staining can be utilized to confirm
the diagnosis. |
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