| Yao Han,Lin Zhen,Baiying Liu,Xiaozhen Zhan,Wenbin Li,Taotao Zhang,Xiangwen Zhang,Guo Zu. Gastric adenocarcinoma with hepatoid adenocarcinoma: A case report and literature review. Oncol Transl Med, 2018, 4: 35-37. |
| 胃腺癌伴肝样腺癌：1例病例报道并文献复习 |
| Gastric adenocarcinoma with hepatoid adenocarcinoma: A case report and literature review |
| Received:November 22, 2017 Revised:February 16, 2018 |
| DOI：10.1007/s10330-017-0244-4 |
| 中文关键词: 胃癌、腺癌、肝样腺癌、免疫组化 |
| 英文关键词: gastric cancer; adenocarcinoma; hepatoid; immunohistochemistry |
| 基金项目: |
| Author Name | Affiliation | E-mail | | Yao Han | Department of Gastroenterology,Dalian Municipal Central Hospital | hanyaomvp1@163.com | | Lin Zhen | Department of Gastroenterology,Dalian Municipal Central Hospital | | | Baiying Liu | Department of Gastroenterology,Dalian Municipal Central Hospital | | | Xiaozhen Zhan | Department of Gastroenterology,Dalian Municipal Central Hospital | | | Wenbin Li | Department of Gastroenterology,Dalian Municipal Central Hospital | | | Taotao Zhang | Department of Gastroenterology,Dalian Municipal Central Hospital | | | Xiangwen Zhang | Department of Gastroenterology,Dalian Municipal Central Hospital | | | Guo Zu* | Department of Gastroenterology,Dalian Municipal Central Hospital | zushanghai@163.com |
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| 中文摘要: |
| 目的：胃的肝样腺癌非常罕见，在以往全球文献中只有少数病例报道。在本报告中，我们描述了一例病例和文献回顾，以提高我们对疾病的认识，减少误诊，并为其治疗和预后提供证据。
方法：我们分享了一个胃肝样腺癌的罕见病例，是一名68岁的中国男性患者，由于上腹部不明原因的疼痛而入院。 体格检查和实验室血液检查未见明显异常。 对比增强计算机断层扫描显示胃窦腔3.0 cm×3.0 cm肿块，邻近器官无转移。
结果：我们对患者进行了根治性胃切除术，术后组织病理学显示中度分化腺癌部分为肝样腺癌。
结论：胃肝样腺癌是临床少见的恶性肿瘤，它的诊断标准主要取决于临床表现，影像学和组织病理学发现。病理形态学和免疫组织化学染色可以用来辅助诊断。 |
| 英文摘要: |
| Objective Hepatoid adenocarcinoma of the stomach is exceedingly rare. Only a few cases have been
reported worldwide. In this report, we describe our pathological findings along with a review of the literature
to improve our understanding of the disease and prevent misdiagnosis, as well as to provide evidence for
its treatment and prognosis.
Methods A 68-year-old male patient was admitted to our hospital (Dalian Municipal Central Hospital,
Dalian, China) complaining of upper abdominal pain. Physical examination and regular laboratory blood
tests showed no obvious abnormalities. A contrast-enhanced computed tomography scan displayed a 3.0
cm × 3.0 cm mass in the gastric antrum, but no metastasis was found in the adjacent organs.
Results A radical gastrectomy was performed and postoperative histopathology showed a moderately
differentiated adenocarcinoma with partial hepatoid adenocarcinoma.
Conclusion Hepatoid adenocarcinoma of the stomach is a rare malignant neoplasm. The diagnostic
criteria for hepatoid adenocarcinoma of the stomach depends mainly on the clinical, radiographic, and
histopathological findings. Pathomorphology and immunohistochemical staining can be utilized to confirm
the diagnosis. |
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