| Fuli Zhang,Yadi Wang,Weidong Xu,Huayong Jiang,Junmao Gao,Qingzhi Liu,Na Lu,Diandian Chen,Bo Yao,Jun Hou,Heliang He,Jianping Chen. Comparison of the effects of two types of multileaf collimators on tumor control probability in radiotherapy for breast cancer after conservative surgery based on the EUD model. Oncol Transl Med, 2017, 3: 77-81. |
| Comparison of the effects of two types of multileaf collimators on tumor control probability in radiotherapy for breast cancer after conservative surgery based on the EUD model |
| Received:January 02, 2017 Revised:May 01, 2017 |
| View Full Text View/Add Comment Download reader |
| KeyWord:tumor control probability (TCP); breast cancer; radiobiology; volumetric modulated arc therapy (VMAT) |
| Author Name | Affiliation | E-mail | | Fuli Zhang | Radiation Oncology Department,The PLA Army General Hospital of China,No. 5,Nanmencang,Dongcheng | radiozfli@163.com | | Yadi Wang | Radiation Oncology Department,The PLA Army General Hospital of China,No. 5,Nanmencang,Dongcheng | wangyadi@hotmail.com | | Weidong Xu | Radiation Oncology Department,The PLA Army General Hospital of China,No. 5,Nanmencang,Dongcheng | | | Huayong Jiang | Radiation Oncology Department,The PLA Army General Hospital of China,No. 5,Nanmencang,Dongcheng | | | Junmao Gao | Radiation Oncology Department,The PLA Army General Hospital of China,No. 5,Nanmencang,Dongcheng | | | Qingzhi Liu | Radiation Oncology Department,The PLA Army General Hospital of China,No. 5,Nanmencang,Dongcheng | | | Na Lu | Radiation Oncology Department,The PLA Army General Hospital of China,No. 5,Nanmencang,Dongcheng | | | Diandian Chen | Radiation Oncology Department,The PLA Army General Hospital of China,No. 5,Nanmencang,Dongcheng | | | Bo Yao | Radiation Oncology Department,The PLA Army General Hospital of China,No. 5,Nanmencang,Dongcheng | | | Jun Hou | Radiation Oncology Department,The PLA Army General Hospital of China,No. 5,Nanmencang,Dongcheng | | | Heliang He | Radiation Oncology Department,The PLA Army General Hospital of China,No. 5,Nanmencang,Dongcheng | | | Jianping Chen | Radiation Oncology Department,The PLA Army General Hospital of China,No. 5,Nanmencang,Dongcheng | |
|
| Hits: 7831 |
| Download times: 8810 |
| Abstract: |
| Objective To compute and compare the tumor control probability (TCP) of volumetric modulated arc
therapy (VMAT) for breast cancer after conservative surgery based on two types of multileaf collimator
(MLC) through a retrospective planning study.
Methods For a group of 9 patients diagnosed with left breast cancer, VMAT plan based on Agility MLC
and beam modulator (BM) MLC were designed. The prescription dose was 50 Gy covering at least 95% of
the planning target volume, 2 Gy per fraction. TCPs were calculated according to dose-volume histogram
(DVH) analysis.
Results The TCP of the BM VMAT plan was slightly higher than that of the Agility VMAT plan (94.61% vs
94.23%) but was inferior with respect to delivery efficiency; the delivery time was reduced for Agility VMAT
plan by 35% compared to BM VMAT plan.
Conclusion For breast cancer radiation therapy after conservative surgery, BM VMAT plans provide
slightly higher TCP while the delivery of Agility VMAT plans is significantly faster than the BM VMAT plans. |
| Close |
|
|
|