RuoBing Liu,KaiYan Li,Hong-Chang Luo,Wei Zhang,Ting-Ting Zhang,Meng Gao,Wen-Hui Zha,Xin-Wu Cui,Youbin Deng. Ultrasound-guided percutaneous microwave ablation for small liver cancers adjacent to large vessels: long-term outcomes and strategies. Oncol Transl Med, 2017, 3: 57-64.
Ultrasound-guided percutaneous microwave ablation for small liver cancers adjacent to large vessels: long-term outcomes and strategies
Received:October 09, 2016  Revised:October 09, 2016
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KeyWord:ultrasound (US); liver cancer; percutaneous microwave ablation (MWA)
Author NameAffiliationE-mail
RuoBing Liu Department of Medical Ultrasound, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China Liky20006@126.com 
KaiYan Li Department of Medical Ultrasound, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China Liky20006@126.com 
Hong-Chang Luo Department of Medical Ultrasound, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China Liky20006@126.com 
Wei Zhang Department of Medical Ultrasound, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China Liky20006@126.com 
Ting-Ting Zhang Department of Medical Ultrasound, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China Liky20006@126.com 
Meng Gao Department of Medical Ultrasound, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China Liky20006@126.com 
Wen-Hui Zha Department of Medical Ultrasound, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China Liky20006@126.com 
Xin-Wu Cui Department of Medical Ultrasound, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China Liky20006@126.com 
Youbin Deng Department of Medical Ultrasound, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China  
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Abstract:
      Objective The aim of the study was to evaluate the long-term efficacy and safety of percutaneous microwave ablation (MWA) for small hepatic cancers adjacent to large vessels and to investigate the treatment strategies. Methods From March 2009 to July 2015, a total of 86 patients with 94 tumors underwent ultrasound (US)-guided percutaneous MWA, with pathologically proven or clinically diagnosed liver cancers measuring ≤ 3 cm in diameter and located ≤ 10 mm from a major vessel (n = 94). Regular follow-up after MWA was performed to assess treatment efficacy and perioperative complications. Results The complete ablation rate at 1 month after MWA was 93.3% (84/90). The 6-, 9-, 12-, 24-, 36-, 48-, 60-, 72-, and 84-month local recurrence rates were 2.4%, 2.4%, 3.7%, 6.6%, 8.4%, 8.4%, 8.4%, 8.4%, and 8.4%, respectively. There were no major complications. The perioperative special complication rate was 5.32% (5/94), including 3 cases of moderate liver function damage and 2 cases of limited sub-capsular hematoma. Conclusion Percutaneous MWA for small hepatic cancers adjacent to large vessels is feasible, effective, and safe with an acceptable rate of complications. The key point is to strictly follow operative indications and adopt proper treatment strategies.
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