| Qiang Yao,Yan Zhou,Chun-Ni Xun,Ke Min,Jun Jin. Epinephrine use during chemotherapy to treat severe tracheal stenosis secondary to advanced esophageal cancer: A case report and review of the literature. Oncol Transl Med, 2016, 2: 239-241. |
| 肾上腺素联合化疗治疗晚期食管癌引起的严重气管狭窄：一例病案报道及文献复习 |
| Epinephrine use during chemotherapy to treat severe tracheal stenosis secondary to advanced esophageal cancer: A case report and review of the literature |
| Received:May 18, 2016 Revised:September 22, 2016 |
| DOI：10.1007/s10330-016-0159-3 |
| 中文关键词: 气管狭窄，呼吸困难，食管恶性肿瘤，肾上腺素，病案报道 |
| 英文关键词: tracheal stenosis; dyspnea; esophageal cancer; epinephrine |
| 基金项目: |
| Author Name | Affiliation | E-mail | | Qiang Yao | The yixing affiliated Hospital of Jiangsu University | staff1226@yxph.com | | Yan Zhou | The yixing affiliated Hospital of Jiangsu University | staff260@yxph.com | | Chun-Ni Xun | The yixing affiliated Hospital of Jiangsu University | staff911@yxph.com | | Ke Min* | The yixing affiliated Hospital of Jiangsu University | staff804@yxph.com | | Jun Jin | The yixing affiliated Hospital of Jiangsu University | staff813@yxph.com |
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| 中文摘要: |
| 摘要：由肿瘤压迫引起气道狭窄导致的呼吸困难是较难治疗的肿瘤急症。我们报道了一例晚期食管癌患者，56岁男性，因纵膈肿大淋巴结压迫气道引起严重的呼吸困难，我们使用了肾上腺素皮下注射及气道吸入来暂时缓解呼吸困难，同时应用贝伐单抗联合化疗。在治疗5天后呼吸困难明显缓解，2周期治疗后纵膈淋巴结明显缩小，但患者在2月后死于气管大出血。 |
| 英文摘要: |
| Dyspnea from tracheal stenosis due to compression by a tumor is an emergency that complicates therapy
in oncology. We report a case of advanced esophageal cancer in a 56-year-old male who developed severe dyspnea due to airway compression by mediastinal lymph node enlargement. We used epinephrine
by subcutaneous injection and aerosol inhalation to temporarily relieve dyspnea while the patient received
bevacizumab and chemotherapy. The dyspnea had subsided considerably after 5 days, and the mediastinal lymph nodes were significantly reduced after 2 cycles of chemotherapy. However, the patient died of
massive tracheal hemorrhage 2 months later. |
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