Qiang Yao,Yan Zhou,Chun-Ni Xun,Ke Min,Jun Jin. Epinephrine use during chemotherapy to treat severe tracheal stenosis secondary to advanced esophageal cancer: A case report and review of the literature. Oncol Transl Med, 2016, 2: 239-241.
Epinephrine use during chemotherapy to treat severe tracheal stenosis secondary to advanced esophageal cancer: A case report and review of the literature
Received:May 18, 2016  Revised:September 22, 2016
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KeyWord:tracheal stenosis; dyspnea; esophageal cancer; epinephrine
Author NameAffiliationE-mail
Qiang Yao The yixing affiliated Hospital of Jiangsu University staff1226@yxph.com 
Yan Zhou The yixing affiliated Hospital of Jiangsu University staff260@yxph.com 
Chun-Ni Xun The yixing affiliated Hospital of Jiangsu University staff911@yxph.com 
Ke Min The yixing affiliated Hospital of Jiangsu University staff804@yxph.com 
Jun Jin The yixing affiliated Hospital of Jiangsu University staff813@yxph.com 
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Abstract:
      Dyspnea from tracheal stenosis due to compression by a tumor is an emergency that complicates therapy in oncology. We report a case of advanced esophageal cancer in a 56-year-old male who developed severe dyspnea due to airway compression by mediastinal lymph node enlargement. We used epinephrine by subcutaneous injection and aerosol inhalation to temporarily relieve dyspnea while the patient received bevacizumab and chemotherapy. The dyspnea had subsided considerably after 5 days, and the mediastinal lymph nodes were significantly reduced after 2 cycles of chemotherapy. However, the patient died of massive tracheal hemorrhage 2 months later.
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