Yakun He,Guohui Xu,Jin Ren,Bin Feng,Xiaolei Dong,Hao Lu,Changjiu He. Mammography combined with breast dynamic contrast-enhanced-magnetic resonance imaging for the diagnosis of early breast cancer. Oncol Transl Med, 2016, 2: 165-168.
Mammography combined with breast dynamic contrast-enhanced-magnetic resonance imaging for the diagnosis of early breast cancer
Received:March 26, 2016  Revised:July 08, 2016
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KeyWord:breast carcinoma; mammography; nuclear magnetic resonance; dynamic enhancement; time signal curve
Author NameAffiliationE-mail
Yakun He Department of Radiology, Sichuan Cancer Hospital, Chengdu 610041, China hykun_1123@163.com 
Guohui Xu Department of Radiology, Sichuan Cancer Hospital, Chengdu 610041, China xgh0913@hotmail.com 
Jin Ren Department of Radiology, Sichuan Cancer Hospital, Chengdu 610041, China 273795600@qq.com 
Bin Feng Department of Radiology, Sichuan Cancer Hospital, Chengdu 610041, China 5182986@qq.com 
Xiaolei Dong Department of Radiology, Sichuan Cancer Hospital, Chengdu 610041, China 309437466@qq.com 
Hao Lu Department of Radiology, Sichuan Cancer Hospital, Chengdu 610041, China 87772031@qq.com 
Changjiu He Department of Radiology, Sichuan Cancer Hospital, Chengdu 610041, China 40234006@qq.com 
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Abstract:
      Objective: The aim of this study was to investigate the application of mammography combined with breast dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) for the diagnosis of early breast cancer. Methods: Mammography and DCE-MRI were performed for 120 patients with breast cancer (malignant, 102; benign; 18). Results: The sensitivity of mammography for early diagnosis of breast cancer was 66.67%, specificity was 77.78%, and accuracy was 68.33%. The sensitivity of MRI for early diagnosis of breast cancer was 94.12%, specificity was 88.89%, and accuracy was 93.33%. However, the sensitivity of mammography combined with DCE-MRI volume imaging with enhanced water signal (VIEWS) scanning for early diagnosis of breast cancer was 97.06%, specificity was 94.44%, and accuracy was 96.67%. Conclusion: Mammography combined with DCE-MRI increased the sensitivity, specificity, and accuracy of diagnosing early breast cancer.
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