| Department of oncology,Mianyang Central Hospital. Progress in research on the relationships among tumor blood supply patterns. Oncol Transl Med, 2016, 2: 138-141. |
| 肿瘤血管供应模式研究进展 |
| Progress in research on the relationships among tumor blood supply patterns |
| Received:December 27, 2015 Revised:June 13, 2016 |
| DOI：10.1007/s10330-016-0128-x |
| 中文关键词: 肿瘤血液供应 ，肿瘤血管生成，血管生成拟态 |
| 英文关键词: tumor blood supply;angiogenesis; vascular minicry |
| 基金项目: |
| Author Name | Affiliation | E-mail | | Department of oncology* | Author: E-mail:lijie@com,Tel:
★Correspondence to: Du Xiaobo,E-mail: duxiaobo@com Tel: | duxiaobo2005@126.com | | Mianyang Central Hospital | Author: E-mail:lijie@com,Tel:
★Correspondence to: Du Xiaobo,E-mail: duxiaobo@com Tel: | duxiaobo2005@126.com |
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| 中文摘要: |
| 肿瘤细胞的生长、浸润和转移需要血液供应。肿瘤血液供应模式具有多样性,对肿瘤细胞生物学特性具有重要作用。血管生成拟态(VM)的发现丰富了肿瘤血管生成的认识。尽管VM只是肿瘤微循环的一种补充,但其广泛的临床意义和特殊的形成方式成为抗肿瘤血管生成治疗新的研究热点。目前,VM和其他肿瘤血液供应模式之间关系的探索仍处在初级阶段。因此,探索血液供应模式之间的关系,将为抗肿瘤治疗开辟新的方式。 |
| 英文摘要: |
| Tumor cell growth, invasion, and metastasis require a blood supply. The diversity of tumor blood supply
patterns and the biological properties of tumor cells play important roles in these processes. The discovery
of vascular mimicry (VM) has enhanced the understanding of the plasticity of tumor cells and angiogenesis.
VM is only a supplemental form of tumor microcirculation. However, the extensive clinical significance and
special formation of VM have generated new ideas regarding anti-vascular tumor therapy. Currently, the
exploration of the relationship between VM and other blood supply patterns is in the early stages, and many
questions remain unanswered. Further in-depth studies of the relationships among tumor blood supply patterns will identify novel anti-tumor therapeutics. |
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