Lan Yang,Jiaobo Zhu,Xiaoyue Song,Yan Qi,Xiaobin Cui,Feng Li. Human papillomavirus-associated diseases and cancers. Oncol Transl Med, 2015, 1: 109-114. |
Human papillomavirus-associated diseases and cancers |
Received:April 27, 2015 Revised:June 05, 2015 |
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KeyWord:human papillomavirus (HPV); low-risk; high-risk; cancer |
Author Name | Affiliation | E-mail | Lan Yang | Department of Pathology and Key Laboratory for Xinjiang Endemic and Ethnic Diseases,Shihezi University School of Medicine,Shihezi | yl-branda@163.com | Jiaobo Zhu | Department of Pathology and Key Laboratory for Xinjiang Endemic and Ethnic Diseases,Shihezi University School of Medicine,Shihezi | 903667821@qq.com | Xiaoyue Song | Department of Pathology and Key Laboratory for Xinjiang Endemic and Ethnic Diseases,Shihezi University School of Medicine,Shihezi | 251856120@qq.com | Yan Qi | Department of Pathology and Key Laboratory for Xinjiang Endemic and Ethnic Diseases,Shihezi University School of Medicine,Shihezi | 1239936182@qq.com | Xiaobin Cui | Department of Pathology and Key Laboratory for Xinjiang Endemic and Ethnic Diseases,Shihezi University School of Medicine,Shihezi | 342029924@qq.com | Feng Li | Department of Pathology and Key Laboratory for Xinjiang Endemic and Ethnic Diseases,Shihezi University School of Medicine,Shihezi | 2642419294@qq.com |
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Abstract: |
Human papillomaviruses (HPVs) have been detected in cervical cancer cells and skin papilloma cells, which have a variety of types, including low-risk and high-risk types. HPV genome replication requires the host cell’s DNA synthesis machinery, and HPVs encode proteins that maintain differentiated epithelial cells
in a replication-competent state. HPV types are tissue-specific and generally produce different types of lesions, either benign or malignant. This review examines different HPV types and their associated diseases and presents therapeutic options for the treatment of HPV-positive diseases. |
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