| Qingjie Yang,Zhong Li,Ming Guo. A clinical study of thoracic esophageal carcinoma metastasis into abdominal lymph nodes. Oncol Transl Med, 2016, 2: 8-11. |
| 胸段食管癌腹部淋巴结转移规律临床分析 |
| A clinical study of thoracic esophageal carcinoma metastasis into abdominal lymph nodes |
| Received:April 15, 2015 Revised:January 27, 2016 |
| DOI：10.1007/s10330-015-0090-z |
| 中文关键词: 食管癌； 腹腔淋巴结； 转移； 规律 |
| 英文关键词: esophageal carcinoma; abdominal lymph node; metastasis |
| 基金项目: |
| Author Name | Affiliation | E-mail | | Qingjie Yang | Department of Cardiothoracic Surgery, The Affiliated Chenggong of Hospital, Xiamen University, Xiamen 361003, | yqj00001@163.com | | Zhong Li | Department of Cardiothoracic Surgery, The Affiliated Chenggong of Hospital, Xiamen University, Xiamen 361003, | yqj00002@163.com | | Ming Guo* | Department of Cardiothoracic Surgery, The Affiliated Chenggong of Hospital, Xiamen University, Xiamen 361003, | goum174@163.com |
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| 中文摘要: |
| 目的 分析胸段食管癌腹腔淋巴结转移规律。方法 对164例胸段食管癌手术病例的腹腔淋巴结数据进行回顾性分析。结果 胸上、中、下段三组食管癌病例，在浸润深度、分化程度、病理类型、病理分期等基础情况差异无统计学意义，三组的腹腔淋巴结转移率(胸上段6.9% < 胸中段27.4% < 胸下段39.6%)差异无统计学意义。不同浸润深度、分化程度、病理类型间，腹腔淋巴结转移率差异无统计学意义。 结论 食管癌存在特殊的跳跃性淋巴结转移，食管胸上段癌只要侵及粘膜下层即有可能通过毛细淋巴管网向下跳跃性转移致腹腔淋巴结，而绝大多数的食管癌诊断时已达T1b期以上，即肿瘤侵及粘膜层以下，因此并不能说早期胸上段高分化食管癌就不易发生腹腔淋巴结转移，手术时常规行腹腔淋巴结清扫是有必要的。 |
| 英文摘要: |
| Objective: The aim of this study was to analyze the potential of thoracic esophageal carcinoma to metastasize
into abdominal lymph nodes.
Methods: The data on abdominal lymph node metastasis in 164 patients who had undergone resection
of thoracic esophageal carcinoma were analyzed retrospectively and grouped according to tumor position
in the upper, middle, or lower thoracic esophagus. The difference in tumor infiltration depth, differentiation
degree, pathological type, pathological stage, and the metastasis rate in abdominal lymph nodes among
the three groups was evaluated and the correlation of abdominal lymph node metastasis with tumor infiltration
depth, differentiation degree, and pathological type was analyzed.
Results: Clinical characteristics such as tumor infiltration depth, differentiation degree, pathological type,
and pathological stage were not significantly different between the patients with upper, middle, and lower
thoracic esophageal carcinomas. Although there was a difference in the metastasis rate in abdominal
lymph nodes between the three groups (6.9%, 27.4%, and 39.6% for the upper, middle, and lower thoracic
esophageal carcinomas, respectively), it was not statistically significant. There was also no association
between the rate of abdominal lymph node metastasis and tumor infiltration depth, differentiation degree,
and pathological type.
Conclusion: Esophageal carcinoma specifically metastasizes into lymph nodes. If the tumor infiltrates
the upper thoracic submucosa, it could metastasize down to abdominal lymph nodes via the lymphatic capillary
net. The majority of esophageal carcinomas were of T1b or higher pathological stage at the diagnosis,
indicating infiltration of the submucosa. Thus, tumors of the early stage, high degree of differentiation, or
position in the upper thoracic esophagus were not less prone to metastasis into abdominal lymph nodes.
Therefore, routine abdominal lymph node dissection during radical surgery for esophageal carcinoma is
necessary. |
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