| Jun Li,Xiaoguang Xiao,Yao Wei,Yang Li,Man Zou,Shiying Yu,Yuan Chen,Qian Chu. Investigation of quality of life in patients with lung cancer by the EORTC QLQ-C30 (V3.0) Chinese version. Oncol Transl Med, 2015, 1: 125-129. |
| Investigation of quality of life in patients with lung cancer by the EORTC QLQ-C30 (V3.0) Chinese version |
| Received:March 18, 2015 Revised:May 29, 2015 |
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| KeyWord:quality of life; lung cancer; EORTC QLQ-C30; influential factors |
| Author Name | Affiliation | E-mail | | Jun Li | Wuhan Commercial Staff Hospital, Tongji Hospital, Tongji Medical School, Huazhong University of Science and Technology | 2061066383@qq.com | | Xiaoguang Xiao | Tongji Hospital, Tongji Medical School, Huazhong University of Science and Technology | xiaoxg997@aliyun.com | | Yao Wei | Tongji Hospital, Tongji Medical School, Huazhong University of Science and Technology | yaoweioncology@163.com | | Yang Li | Tongji Hospital, Tongji Medical School, Huazhong University of Science and Technology | ffstara@163.com | | Man Zou | Tongji Hospital, Tongji Medical School, Huazhong University of Science and Technology | skyfountain@163.com | | Shiying Yu | Tongji Hospital, Tongji Medical School, Huazhong University of Science and Technology | syyu@tjh.tjmu.edu.cn | | Yuan Chen | Tongji Hospital, Tongji Medical School, Huazhong University of Science and Technology | chenyuan008@163.com | | Qian Chu | Tongji Hospital, Tongji Medical School, Huazhong University of Science and Technology | qianchu@tjh.tjmu.edu.cn |
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| Abstract: |
| Objective To explore quality of life (QOL) and its influencing factors in patients with lung cancer.
Methods A QOL questionnaire (European Organization for Research and Treatment of Cancer [EORTC]
Quality of Life Questionnaire-Core 30 [QLQ-C30] Chinese version) was used with 138 patients with lung
cancer participating in the study. A statistical description of the general characteristics of the patients with
lung cancer was performed. The patients’ QLQ-C30 scores were compared with the reference value for
each dimension. To analyze the influence of QOL in different genders, age groups, and cancer stages, ttests and rank sum tests were used to compare the differences in QOL using a 5% significance level.
Results The QLQ-C30 function scores in PF (physical functioning), EF (emotional functioning), SF (social functioning), and GH (global functioning), and symptom scales in NV (nausea and vomiting), DY (dyspnea), SL (insomnia), and FI (financial difficulties) were significantly different (P < 0.05) in comparison to the
reference values. Female patients were worse than males (P < 0.05) in EF, NV, and DI (diarrhea). The later
the stage of lung cancer, the worse the quality of life became; the functional scales in RF (role functioning),
EF, CF, SF, and GH, and symptom scales in PA (pain), AP (appetite), and SL differences were statistically
significant (P < 0.05).
Conclusion This study aids understanding of the status of the quality of life of Chinese patients with
cancer and might be useful for clinical work, theory research, and health policymakers. |
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