| Jun Li,Xiaoguang Xiao,Yao Wei,Yang Li,Man Zou,Shiying Yu,Yuan Chen,Qian Chu. Investigation of quality of life in patients with lung cancer by the EORTC QLQ-C30 (V3.0) Chinese version. Oncol Transl Med, 2015, 1: 125-129. |
| EORTC QLQ-C30中文版应用于肺癌患者生活质量测评的研究 |
| Investigation of quality of life in patients with lung cancer by the EORTC QLQ-C30 (V3.0) Chinese version |
| Received:March 18, 2015 Revised:May 29, 2015 |
| DOI：10.1007/s10330-015-0079-7 |
| 中文关键词: 生活质量；肺癌；EORTC QLQ-C30；影响因素 |
| 英文关键词: quality of life; lung cancer; EORTC QLQ-C30; influential factors |
| 基金项目:本文受湖北省自然科学基金（No.2013CFB138）和湖北省卫计委科研基金（No. WJ2015Q009）资助。 |
| Author Name | Affiliation | E-mail | | Jun Li | Wuhan Commercial Staff Hospital, Tongji Hospital, Tongji Medical School, Huazhong University of Science and Technology | 2061066383@qq.com | | Xiaoguang Xiao | Tongji Hospital, Tongji Medical School, Huazhong University of Science and Technology | xiaoxg997@aliyun.com | | Yao Wei | Tongji Hospital, Tongji Medical School, Huazhong University of Science and Technology | yaoweioncology@163.com | | Yang Li | Tongji Hospital, Tongji Medical School, Huazhong University of Science and Technology | ffstara@163.com | | Man Zou | Tongji Hospital, Tongji Medical School, Huazhong University of Science and Technology | skyfountain@163.com | | Shiying Yu | Tongji Hospital, Tongji Medical School, Huazhong University of Science and Technology | syyu@tjh.tjmu.edu.cn | | Yuan Chen | Tongji Hospital, Tongji Medical School, Huazhong University of Science and Technology | chenyuan008@163.com | | Qian Chu* | Tongji Hospital, Tongji Medical School, Huazhong University of Science and Technology | qianchu@tjh.tjmu.edu.cn |
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| 中文摘要: |
| 目的：探讨三级甲等医院肿瘤专科住院肺癌患者生活质量状况及其影响因素。方法：采用EORTC生活质量测定量表QLQ-C30（V3.0）中文版对138名肺癌患者进行问卷调查。对入组患者一般特征进行统计描述；在各维度对肺癌患者的生活质量评分与参考值相比较；利用t检验及秩和检验分析不同性别、年龄及分期对生活质量各维度指标影响及差异。结果：肺癌患者总体QLQ-C30得分与参考值比较，功能量表中躯体功能（Physical Functioning，PF）、情绪功能（Emotional Functioning，EF）、社会功能（Social Functioning，SF）及总体健康状况（Global Functioning ，GH），症状量表中恶心与呕吐（Nausea and Vomiting，NV）、呼吸困难（Dyspnea, DY）、失眠（Insomnia,SL）、经济困难（Financial Difficulties，FI）与参考值比较有显著差异（p<0.05）。女性患者在EF、NV、腹泻（Diarrhea，DI）均差于男性（p<0.05）。肺癌分期越晚的患者生活质量越差，其中功能量表中角色功能（Role Functioning，RF）、EF、认知功能（Cognitive Functioning，CF）及SF、GH，症状量表中疼痛（Pain，PA）、食欲丧失（Appetite，AP）及SL差异有统计学意义（p<0．05）。结论: 我国肺癌患者生活质量相对较差，特别是高龄、女性、分期较晚及经济拮据的患者尤为显著。 |
| 英文摘要: |
| Objective To explore quality of life (QOL) and its influencing factors in patients with lung cancer.
Methods A QOL questionnaire (European Organization for Research and Treatment of Cancer [EORTC]
Quality of Life Questionnaire-Core 30 [QLQ-C30] Chinese version) was used with 138 patients with lung
cancer participating in the study. A statistical description of the general characteristics of the patients with
lung cancer was performed. The patients’ QLQ-C30 scores were compared with the reference value for
each dimension. To analyze the influence of QOL in different genders, age groups, and cancer stages, ttests and rank sum tests were used to compare the differences in QOL using a 5% significance level.
Results The QLQ-C30 function scores in PF (physical functioning), EF (emotional functioning), SF (social functioning), and GH (global functioning), and symptom scales in NV (nausea and vomiting), DY (dyspnea), SL (insomnia), and FI (financial difficulties) were significantly different (P < 0.05) in comparison to the
reference values. Female patients were worse than males (P < 0.05) in EF, NV, and DI (diarrhea). The later
the stage of lung cancer, the worse the quality of life became; the functional scales in RF (role functioning),
EF, CF, SF, and GH, and symptom scales in PA (pain), AP (appetite), and SL differences were statistically
significant (P < 0.05).
Conclusion This study aids understanding of the status of the quality of life of Chinese patients with
cancer and might be useful for clinical work, theory research, and health policymakers. |
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