| Fuli Zhang,Huayong Jiang,Weidong Xu,Yadi Wang,Qingzhi Liu,Na Lu,Diandian Chen,Bo Yao. Phantom-based evaluations of two binning algorithms for four-dimensional CT reconstruction in lung cancer radiation therapy. Oncol Transl Med, 2014, 13: 563-566. |
| Phantom-based evaluations of two binning algorithms for four-dimensional CT reconstruction in lung cancer radiation therapy |
| Received:November 03, 2014 Revised:December 09, 2014 |
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| KeyWord:four-dimensional computed tomography (4DCT); phase-binning algorithm; amplitude-binning algorithm; lung cancer |
| Author Name | Affiliation | E-mail | | Fuli Zhang | Department of Radiation Oncology, The Military General Hospital of Beijing PLA | radiozfli@163.com | | Huayong Jiang | Department of Radiation Oncology, The Military General Hospital of Beijing PLA, Beijing 100700, China | | | Weidong Xu | Department of Radiation Oncology, The Military General Hospital of Beijing PLA, Beijing 100700, China | | | Yadi Wang | Department of Radiation Oncology, The Military General Hospital of Beijing PLA, Beijing 100700, China | | | Qingzhi Liu | Department of Radiation Oncology, The Military General Hospital of Beijing PLA, Beijing 100700, China | | | Na Lu | Department of Radiation Oncology, The Military General Hospital of Beijing PLA, Beijing 100700, China | | | Diandian Chen | Department of Radiation Oncology, The Military General Hospital of Beijing PLA, Beijing 100700, China | | | Bo Yao | Department of Radiation Oncology, The Military General Hospital of Beijing PLA, Beijing 100700, China | |
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| Abstract: |
| Objective: The purpose of this study was to evaluate the performance of the phase-binning algorithm and amplitude-binning algorithm for four-dimensional computed tomography (4DCT) reconstruction in lung cancer radiation therapy. Methods: Quasar phantom data were used for evaluation. A phantom of known geometry was mounted on a four-dimensional (4D) motion platform programmed with twelve respiratory waves (twelve lung patients trajectories) and scanned with a Philips Brilliance Big bore 16-slice CT simulator. The 4DCT images were reconstructed using both phase- and amplitude-binning algorithms. Internal target volumes (ITVs) of the phase- and amplitude-binned image sets were compared by evaluation of shape and volume distortions. Results: The phantom experiments illustrated that, as expected, maximum inhalation occurred at the 0% amplitude and maximum exhalation occurred at the 50% amplitude of the amplitude-binned 4DCT image sets. The amplitude-binned algorithm rendered smaller ITV than the phase-binning algorithm. Conclusion: The amplitude-binning algorithm for 4DCT reconstruction may have a potential advantage in reducing the margin and protecting normal lung tissue from unnecessary irradiation. |
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