| Bing Li,Yuchen Bao,Bin Chen,Songwen Zhou. Therapy for non-small-cell lung cancer patients with brain metastases. Oncol Transl Med, 2014, 13: 483-488. |
| 非小细胞肺患者脑转移的治疗 |
| Therapy for non-small-cell lung cancer patients with brain metastases |
| Received:August 19, 2014 Revised:September 25, 2014 |
| DOI：10.1007/s10330-014-0048-6 |
| 中文关键词: 非小细胞肺癌；脑转移；全脑放疗；手术；立体定向放射治疗；化疗；靶向治疗 |
| 英文关键词: non?small?cell lung cancer (NSCLC); brain metastasis; whole?brain radiotherapy; surgery; stereotactic radiotherapy; chemotherapy; targeted therapy |
| 基金项目: |
| Author Name | Affiliation | E-mail | | Bing Li | Department of Medical Oncology,Shanghai Pulmonary Hospital,Tongji University School of Medicine | libing044162@163.com | | Yuchen Bao | Department of Medical Oncology,Shanghai Pulmonary Hospital,Tongji University School of Medicine | | | Bin Chen | Department of Medical Oncology,Shanghai Pulmonary Hospital,Tongji University School of Medicine | | | Songwen Zhou* | Department of Medical Oncology,Shanghai Pulmonary Hospital,Tongji University School of Medicine | zhou_songwen@126.com |
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| 中文摘要: |
| 非小细胞肺癌患者的脑转移的预后通常较差，需要有效的治疗手段改善其预后。全脑放疗，手术，立体定向放射治疗，化疗和靶向治疗是脑转移瘤的主要治疗方法。本文针对上述五个治疗策略展开综述，并着重介绍了靶向治疗 |
| 英文摘要: |
| Brain metastasis is a major cause of poor prognosis and high mortality for non-small cell lung cancer patients. The prognosis of non-small-cell lung cancer (NSCLC) patients with brain metastasis is generally poor and more effective treatment is required to improve their prognosis. Whole-brain radiotherapy, surgery, stereotactic radiosurgery, chemotherapy and targeted therapy are the main treatment for brain metastasis. This review focuses on the five therapeutic strategy and in particular, on targeted therapy. |
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