Yafei Zhang,Xuyan Mao,Jichun Zheng,Zhanfei Zu,Gaoping Mao,Shoubin Ning. Small intestine adenocarcinoma associated with Peutz-Jeghers syndrome: a report of 5 cases and literature review. Oncol Transl Med, 2014, 13: 337-340. |
Small intestine adenocarcinoma associated with Peutz-Jeghers syndrome: a report of 5 cases and literature review |
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KeyWord:small intestine adenocarcinoma; Peutz-Jeghers syndrome (PJS); histopathology; clinical surveillance |
Author Name | Affiliation | Yafei Zhang | Department of Gastroenterology, General Hospital of Air Force, PLA, Beijing 100142, China | Xuyan Mao | Department of Gastroenterology, General Hospital of Air Force, PLA, Beijing 100143, China | Jichun Zheng | Department of Pathology, General Hospital of Air Force, PLA, Beijing 100142, China | Zhanfei Zu | Department of Gastroenterology, General Hospital of Air Force, PLA, Beijing 100145, China | Gaoping Mao | Department of Gastroenterology, General Hospital of Air Force, PLA, Beijing 100146, China | Shoubin Ning | Department of Gastroenterology, General Hospital of Air Force, PLA, Beijing 100147, China |
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Abstract: |
Peutz-Jeghers syndrome (PJS) is a rare autosomal dominant inherited disorder, manifested as multiple hamartomatous polyps of gastrointestinal tract, mucocutaneous pigmentations and increased risk of cancers. In this manuscript, we reported five cases of small intestinal carcinoma associated with the PJS. All the five patients have a history of PJS and postoperative pathological examination confirmed the diagnosis of small intestinal carcinoma. Histopathological features and recommended surveillance were additionally discussed. |
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