Fei Gao,Lin Jia,Xiaobo Du,Yun Wang,Jianjun Han. Relationship between hepatitis B virus infection and hepatic metastasis in non-small cell lung cancer. Oncol Transl Med, 2014, 13: 212-214. |
Relationship between hepatitis B virus infection and hepatic metastasis in non-small cell lung cancer |
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KeyWord:hepatitis B virus (HBV); non-small cell lung cancer (NSCLC); hepatic metastasis |
Author Name | Affiliation | Fei Gao | Department of Oncology, The Third Hospital of Mianyang, Mianyang 621000, China | Lin Jia | Department of Oncology, The Third Hospital of Mianyang, Mianyang 621001, China | Xiaobo Du | Department of Oncology, The Central Hospital of Mianyang, Mianyang 621600, China | Yun Wang | Department of Oncology, The Third Hospital of Mianyang, Mianyang 621003, China | Jianjun Han | Department of Oncology, The Third Hospital of Mianyang, Mianyang 621004, China |
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Abstract: |
Objective: The purpose of the study was to explore the relationship between hepatitis B virus (HBV) infection and hepatic metastasis in non-small cell lung cancer (NSCLC). Methods: Four hundred and eighty cases of NSCLC were retrospectively analyzed from January 2003 to January 2010, and the prevalence of hepatic metastasis of NSCLC in patients with and without hepatitis B virus infection were compared. Results: In the HBV carriers’ group, the prevalence of synchronous hepatic metastasis and metachronous hepatic metastasis were 13.2% and 5.9%, respectively. Meanwhile in the non-HBV group, those were 21.6% and 9.5% respectively. A significant difference between the two groups was found (P < 0.05). Conclusion: The prevalence of synchronous hepatic metastasis and metachronous hepatic metastasis in non-small cell lung cancer with HBV infection are lower than those in non-HBV infection group. Hepatic metastasis is infrequent in HBV infected cases of NSCLC. |
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