Ze Ouyang,Weili Tao,Shiying Yu,Man Zou. Advances in pharmacotherapies in cancer-related cachexia. Oncol Transl Med, 2023, 9: 15-21.
Advances in pharmacotherapies in cancer-related cachexia
Received:November 04, 2022  Revised:February 27, 2023
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KeyWord:cancer; cachexia; muscle wasting; mechanism; drug therapy
Author NameAffiliationE-mail
Ze Ouyang Department of Oncology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology ouyz20@163.com 
Weili Tao Department of Oncology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology  
Shiying Yu Department of Oncology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology  
Man Zou Department of Oncology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology skyfountain@163.com 
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Abstract:
      Cancer-related cachexia is highly prevalent in patients with advanced cancer, affecting approximately 50%– 80% of patients and seriously interfering with active therapy, quality of life, and survival time. There are currently no effective treatments for cachexia. Therefore, new therapeutic strategies are required. In recent years, advances in understanding the mechanisms underlying cachexia have been made, and new drugs have been developed to combat cachexia muscle wasting and weight loss due to cancer. In this systematic review, we discuss these novel targets and drug treatments.
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