Xiaoying Quan,Xiaoyan Chen,Lei Lei,Xiaoli Jia,Chunzhi Wu,Bin Ye. Case report of a mixed pulmonary large cell neuroendocrine carcinoma. Oncol Transl Med, 2022, 8: 311-313.
Case report of a mixed pulmonary large cell neuroendocrine carcinoma
Received:January 17, 2022  Revised:December 20, 2022
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KeyWord:pulmonary large cell neuroendocrine carcinoma; pulmonary adenocarcinoma; diagnosis; treatment
Author NameAffiliationE-mail
Xiaoying Quan Department of Medical Oncology, The Sixth People''''s Hospital of Chengdu 1193084163@qq.com 
Xiaoyan Chen Department of Medical Oncology, The Sixth People''''s Hospital of Chengdu  
Lei Lei Department of Medical Oncology, The Sixth People''''s Hospital of Chengdu  
Xiaoli Jia Department of Medical Oncology, The Sixth People''''s Hospital of Chengdu  
Chunzhi Wu Department of Medical Oncology, The Sixth People''''s Hospital of Chengdu  
Bin Ye Department of Medical Oncology, The Sixth People''''s Hospital of Chengdu 354539616@qq.com 
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Abstract:
      A 57 year-old male patient was found to have a lesion in the middle lobe of his right lung using chest computed tomography (CT). Tumor cells were detected, and surgical excision was performed. The patient was diagnosed with mixed large cell neuroendocrine carcinoma, and underwent six cycles of a chemotherapy regimen comprising etoposide combined with cisplatin. Genetic testing revealed an EGFR mutation, which prompted oxitinib-targeted therapy. To date, no signs of recurrence or metastasis have been reported.
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