Wenting Li,Shiying Yu. Research progress on immune checkpoint inhibitors in neoadjuvant therapy for gastric cancer. Oncol Transl Med, 2022, 8: 74-82.
Research progress on immune checkpoint inhibitors in neoadjuvant therapy for gastric cancer
Received:January 13, 2022  Revised:April 20, 2022
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KeyWord:gastric cancer; immune checkpoint inhibitors (ICIs); neoadjuvant therapy
Author NameAffiliationE-mail
Wenting Li Department of Oncology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology liwtpx@163.com 
Shiying Yu Department of Oncology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology syyu@tjh.tjmu.edu.cn 
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Abstract:
      In recent years, immune checkpoint inhibitors (ICIs) have become an important treatment strategy for advanced gastric cancer. Immunotherapy has gradually transitioned from a later-line to a first-line treatment for advanced gastric cancer. Simultaneously, more and more researchers have begun to pay attention to whether immunotherapy can be used for resectable gastric cancer. The current use of ICIs in the neoadjuvant treatment of gastric cancer is still in its exploratory stage, with a number of clinical trials currently underway. However, the available data show good application prospects. This article reviews the research progress on ICIs in the neoadjuvant therapy for gastric cancer and evokes some unresolved problems.
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