Xiaoli Zou,Changzhi Zhao,Tao Wang,Li Jia,Zhongyi Feng,Xiaoguang Wang,Lei Wei,Xiaobei Liu. The clinical efficacy of percutaneous ethanol-lipiodol injection (PEI) combined with high-intensity focused ultrasound (HIFU) for small hepatocellularcarcinomain special or high-risk locations. Oncol Transl Med, 2021, 7: 172-176.
The clinical efficacy of percutaneous ethanol-lipiodol injection (PEI) combined with high-intensity focused ultrasound (HIFU) for small hepatocellularcarcinomain special or high-risk locations
Received:January 08, 2021  Revised:August 10, 2021
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KeyWord:hepatocellular carcinoma; special location; high-intensity focused ultrasound (HIFU); percutaneous ethanol-lipiodol injection (PEI); ethanol; lipiodol
Author NameAffiliationE-mail
Xiaoli Zou Department of Ultrasound Imaging, The Affiliated Dalian Municipal Friendship Hospital of Dalian Medical University, Dalian 116001, China 1324470905@qq.com 
Changzhi Zhao Department of Hepatobiliary Surgery, The Affiliated Dalian Municipal Friendship Hospital of Dalian Medical University, Dalian 116001, China  
Tao Wang Department of Hepatobiliary Surgery, The Affiliated Dalian Municipal Friendship Hospital of Dalian Medical University, Dalian 116001, China  
Li Jia Department of Ultrasound Imaging, The Affiliated Dalian Municipal Friendship Hospital of Dalian Medical University, Dalian 116001, China  
Zhongyi Feng Department of Hepatobiliary Surgery, The Affiliated Dalian Municipal Friendship Hospital of Dalian Medical University, Dalian 116001, China  
Xiaoguang Wang Department of Hepatobiliary Surgery, The Affiliated Dalian Municipal Friendship Hospital of Dalian Medical University, Dalian 116001, China  
Lei Wei Department of Hepatobiliary Surgery, The Affiliated Dalian Municipal Friendship Hospital of Dalian Medical University, Dalian 116001, China  
Xiaobei Liu Department of Hepatobiliary Surgery, The Affiliated Dalian Municipal Friendship Hospital of Dalian Medical University, Dalian 116001, China 13942077177@139.com 
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Abstract:
      Objective: The objective of this study was to explore the short-term effects and postoperative complications of ultrasound-guided percutaneous ethanol-lipiodol injection (PEI) combined with high-intensity focused ultrasound (HIFU) for the treatment of small hepatocellular carcinoma in a special or high-risk location. Methods: Forty patients with small liver cancer in a special or high-risk location were randomly divided into two groups: 20 patients were treated with PEI combined with HIFU (P + H group), and 20 patients were treated with HIFU alone (H group). There were no significant differences in average age, liver function, tumor location, tumor number, or tumor size between the two groups (P > 0.05). Results: Significant differences were observed in ablation parameters between the two groups (P < 0.05). Under the same power, ablation rates of the P + H group were significantly higher than those in the H group, and postoperative complications in the P + H group were significantly lower than those in the H group (P < 0.05). Conclusion: The combination of PEI and HIFU has better clinical value than HIFU alone for small-cell liver cancer in special or high-risk locations.
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