| Lei Zhou,Dongbo Liu. Local definitive intensity-modulated radiation therapy recommended for patients initially diagnosed with nasopharyngeal carcinoma with distant metastasis after an effective systemic chemotherapy. Oncol Transl Med, 2018, 4: 234-237. |
| Local definitive intensity-modulated radiation therapy recommended for patients initially diagnosed with nasopharyngeal carcinoma with distant metastasis after an effective systemic chemotherapy |
| Received:August 30, 2018 Revised:October 19, 2018 |
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| KeyWord:nasopharyngeal carcinoma (NPC); metastasis; intensity-modulated radiation therapy (IMRT) |
| Author Name | Affiliation | E-mail | | Lei Zhou | Cancer Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology | dbliutj@163.com | | Dongbo Liu | Cancer Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology | dbliutj@163.com |
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| Abstract: |
| Objective: The aim of the study was to propose a hypothesis that local definitive intensity-modulated radiation therapy (IMRT) should be recommended for initially diagnosed metastatic nasopharyngeal carcinoma (NPC) and demonstrate its feasibility. Methods: Recently published papers on local definitive radiotherapy for initially diagnosed metastatic NPC were reviewed to propose a hypothesis. Results: Several studies revealed the survival benefits of adding local definitive radiotherapy to the systemic chemotherapy in patients initially diagnosed with metastatic NPC. Conclusion: We suggested that local definitive IMRT should be recommended in patients initially diagnosed with NPC with distant metastasis after an effective systemic chemotherapy, which may possibly prolong their survival time and potentially treat the disease. |
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