Qian Shen,Yuping Yin,Lihong Zhang,Dongbo Liu,Shiying Yu,Huihua Xiong,Xianglin Yuan,Yongsheng Jiang. Recurrent ascites due to spontaneous intraperitoneal bladder rupture after pelvic radiation therapy for cervical cancer. Oncol Transl Med, 2018, 4: 72-75.
Recurrent ascites due to spontaneous intraperitoneal bladder rupture after pelvic radiation therapy for cervical cancer
Received:April 13, 2018  Revised:May 09, 2018
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KeyWord:radiation cystitis; spontaneous intraperitoneal bladder rupture; recurrent ascites; cervical cancer
Author NameAffiliationE-mail
Qian Shen Department of Oncology,Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Road, Wuhan, China, 430030. shenqianoncology@163.com 
Yuping Yin Department of Gastrointestinal Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology  
Lihong Zhang Department of Oncology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology  
Dongbo Liu Department of Oncology,Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology  
Shiying Yu Department of Oncology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology  
Huihua Xiong Department of Oncology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology  
Xianglin Yuan Department of Oncology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology  
Yongsheng Jiang Department of Oncology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology ysjiang.china@163.com 
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Abstract:
      Radiation cystitis is one of the major complications following radiotherapy for cervical cancer. However, spontaneous intraperitoneal bladder rupture as a result of radiation cystitis following radiotherapy for cervical cancer is extremely rare. Case presentation: We report a 52-year-old patient who received radiation therapy for cervical cancer 15 years prior to presentation. Eight years prior to presentation, she developed recurrent abdominal distension, oliguria, and ascites. Following ascites drainage and supportive treatment, all symptoms were relieved. However, all symptoms subsequently recurred every few months. The patient underwent exploratory laparotomy twice. The first exploratory laparotomy in July 2015 found no specific abnormalities. The second exploratory laparotomy in November 2016 found an intraperitoneal bladder rupture, and the patient underwent surgical repair. The ascites subsequently resolved. Conclusion: The occurrence of spontaneous intraperitoneal bladder rupture after radiation therapy for cervical cancer is rare. The prognosis is good when diagnosis and treatment are prompt.
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