| Shan Hu. Preliminary clinical application of an adaptive iterative statistical reconstruction algorithm inhead and neck computed tomography angiography with low tube voltage and a low concentration of contrast medium. Oncol Transl Med, 2015, 1: 171-176. |
| Preliminary clinical application of an adaptive iterative statistical reconstruction algorithm inhead and neck computed tomography angiography with low tube voltage and a low concentration of contrast medium |
| Received:June 19, 2015 Revised:July 25, 2015 |
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| KeyWord:low concentration contrast medium; head and neck computed tomography angiography; adaptive iterative statistical reconstruction algorithm |
| Author Name | Affiliation | E-mail | | Shan Hu | The department of Radiology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, 106 Zhongshan Er Road, Guangzhou 510080 | 27355432@qq.com |
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| Abstract: |
| Objective To evaluate the feasibility of using a low concentration of contrast medium (Visipaque 270
mgI/mL), low tube voltage, and an advanced image reconstruction algorithm in head and neck computed
tomography angiography (CTA).
Methods Forty patients (22 men and 18 women; average age 48.7 ± 14.25 years; average body mass
index 23.9 ± 3.7 kg/m2) undergoing CTA for suspected vascular diseases were randomly assigned into
two groups. Group A (n = 20) was administered 370 mgI/mL contrast medium, and group B (n = 20) was
administered 270 mgI/mL contrast medium. Both groups were administered at a rate of 4.8 mL/s and an
injection volume of 0.8 mL/kg. Images of group A were obtained with 120 kVp and filtered back projection
(FBP) reconstruction, whereas images of group B were obtained with 80 kVp and 80% adaptive iterative
statistical reconstruction algorithm (ASiR). The CT values and standard deviations of intracranial arteries
and image noise on the corona radiata were measured to calculate the contrast-to-noise ratio (CNR) and
signal-to-noise ratio (SNR). The beam-hardening artifacts (BHAs) around the skull base were calculated.
Two readers evaluated the image quality with volume rendered images using scores from 1 to 5. The values
between the two groups were statistically compared.
Results The mean CT value of the intracranial arteries in group B was significantly higher than that in
group A (P < 0.001). The CNR and SNR values in group B were also statistically higher than those in group
A (P < 0.001). Image noise and BHAs were not significantly different between the two groups. The image
quality score of VR images of in group B was significantly higher than that in group A (P = 0.001). However,
the quality scores of axial enhancement images in group B became significantly smaller than those in group
A (P< 0.001). The CT dose index volume and dose-length product were decreased by 63.8% and 64%,
respectively, in group B (P < 0.001 for both).
Conclusion Visipaque combined with 80 kVp and 80% ASiR provided similar image quality in intracranial
CTA with 64% radiation dose reduction compared with the use of Iopamidol, 120 kVp, and FBP reconstruction. |
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