Lan Yang,Jiaobo Zhu,Xiaoyue Song,Yan Qi,Xiaobin Cui,Feng Li. Human papillomavirus-associated diseases and cancers. Oncol Transl Med, 2015, 1: 109-114.
Human papillomavirus-associated diseases and cancers
Received:April 27, 2015  Revised:June 05, 2015
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KeyWord:human papillomavirus (HPV); low-risk; high-risk; cancer
Author NameAffiliationE-mail
Lan Yang Department of Pathology and Key Laboratory for Xinjiang Endemic and Ethnic Diseases,Shihezi University School of Medicine,Shihezi yl-branda@163.com 
Jiaobo Zhu Department of Pathology and Key Laboratory for Xinjiang Endemic and Ethnic Diseases,Shihezi University School of Medicine,Shihezi 903667821@qq.com 
Xiaoyue Song Department of Pathology and Key Laboratory for Xinjiang Endemic and Ethnic Diseases,Shihezi University School of Medicine,Shihezi 251856120@qq.com 
Yan Qi Department of Pathology and Key Laboratory for Xinjiang Endemic and Ethnic Diseases,Shihezi University School of Medicine,Shihezi 1239936182@qq.com 
Xiaobin Cui Department of Pathology and Key Laboratory for Xinjiang Endemic and Ethnic Diseases,Shihezi University School of Medicine,Shihezi 342029924@qq.com 
Feng Li Department of Pathology and Key Laboratory for Xinjiang Endemic and Ethnic Diseases,Shihezi University School of Medicine,Shihezi 2642419294@qq.com 
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Abstract:
      Human papillomaviruses (HPVs) have been detected in cervical cancer cells and skin papilloma cells, which have a variety of types, including low-risk and high-risk types. HPV genome replication requires the host cell’s DNA synthesis machinery, and HPVs encode proteins that maintain differentiated epithelial cells in a replication-competent state. HPV types are tissue-specific and generally produce different types of lesions, either benign or malignant. This review examines different HPV types and their associated diseases and presents therapeutic options for the treatment of HPV-positive diseases.
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