Jun Li,Xiaoguang Xiao,Yao Wei,Yang Li,Man Zou,Shiying Yu,Yuan Chen,Qian Chu. Investigation of quality of life in patients with lung cancer by the EORTC QLQ-C30 (V3.0) Chinese version. Oncol Transl Med, 2015, 1: 125-129.
Investigation of quality of life in patients with lung cancer by the EORTC QLQ-C30 (V3.0) Chinese version
Received:March 18, 2015  Revised:May 29, 2015
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KeyWord:quality of life; lung cancer; EORTC QLQ-C30; influential factors
Author NameAffiliationE-mail
Jun Li Wuhan Commercial Staff Hospital, Tongji Hospital, Tongji Medical School, Huazhong University of Science and Technology 2061066383@qq.com 
Xiaoguang Xiao Tongji Hospital, Tongji Medical School, Huazhong University of Science and Technology xiaoxg997@aliyun.com 
Yao Wei Tongji Hospital, Tongji Medical School, Huazhong University of Science and Technology yaoweioncology@163.com 
Yang Li Tongji Hospital, Tongji Medical School, Huazhong University of Science and Technology ffstara@163.com 
Man Zou Tongji Hospital, Tongji Medical School, Huazhong University of Science and Technology skyfountain@163.com 
Shiying Yu Tongji Hospital, Tongji Medical School, Huazhong University of Science and Technology syyu@tjh.tjmu.edu.cn 
Yuan Chen Tongji Hospital, Tongji Medical School, Huazhong University of Science and Technology chenyuan008@163.com 
Qian Chu Tongji Hospital, Tongji Medical School, Huazhong University of Science and Technology qianchu@tjh.tjmu.edu.cn 
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Abstract:
      Objective To explore quality of life (QOL) and its influencing factors in patients with lung cancer. Methods A QOL questionnaire (European Organization for Research and Treatment of Cancer [EORTC] Quality of Life Questionnaire-Core 30 [QLQ-C30] Chinese version) was used with 138 patients with lung cancer participating in the study. A statistical description of the general characteristics of the patients with lung cancer was performed. The patients’ QLQ-C30 scores were compared with the reference value for each dimension. To analyze the influence of QOL in different genders, age groups, and cancer stages, ttests and rank sum tests were used to compare the differences in QOL using a 5% significance level. Results The QLQ-C30 function scores in PF (physical functioning), EF (emotional functioning), SF (social functioning), and GH (global functioning), and symptom scales in NV (nausea and vomiting), DY (dyspnea), SL (insomnia), and FI (financial difficulties) were significantly different (P < 0.05) in comparison to the reference values. Female patients were worse than males (P < 0.05) in EF, NV, and DI (diarrhea). The later the stage of lung cancer, the worse the quality of life became; the functional scales in RF (role functioning), EF, CF, SF, and GH, and symptom scales in PA (pain), AP (appetite), and SL differences were statistically significant (P < 0.05). Conclusion This study aids understanding of the status of the quality of life of Chinese patients with cancer and might be useful for clinical work, theory research, and health policymakers.
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