| Kun yan,Yanyan Ge,Youhong Ding,Shiguang Yan,Xiangyang Li. Peripheral primitive neuroectodermal tumors: a rare case report. Oncol Transl Med, 2014, 13: 392-394. |
| Peripheral primitive neuroectodermal tumors: a rare case report |
| Received:June 22, 2014 Revised:July 31, 2014 |
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| KeyWord:peripheral primitive neuroectodermal tumors; immunohistochemistry; adjuvant chemoradiation |
| Author Name | Affiliation | E-mail | | Kun yan | Cancer Center, The 82nd Hospital of the Chinese PLA, Huai`an | 1992394813@qq.com | | Yanyan Ge | Anesthesia department,The nd Hospital of the Chinese PLA,Huai`an | | | Youhong Ding | Cancer Center,The nd Hospital of the Chinese PLA,Huai`an | | | Shiguang Yan | Cancer Center,The nd Hospital of the Chinese PLA,Huai`an | | | Xiangyang Li | Cancer Center,The nd Hospital of the Chinese PLA,Huai`an | 1992394813@qq.com |
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| Abstract: |
| We aimed to explore the diagnosis and treatment of peripheral primitive neuroectodermal tumors (pPNETs). We retrospectively analyzed the diagnosis and treatment process of a patient who was diagnosed with pPNETs by pathology. This case was a man with soft masses arising from the left chest wall near the armpit and left supraclavicular of a 47-year-old man. The patient mainly presented with the masses which increasing gradually with obvious pain. Needle biopsy showed that they were both metastatic adenocarcinoma. Ultrasonography B revealed blood flow of these two low density placeholders can be seen in the signal, not oppression axillary and vein. Radical resection of the masses were performed. Histopathologic study and immunohistochemistry (IHC) confirmed the masses to be peripheral primitive neuroectodermal tumors. pPNETs is a rare malignant small round cell tumor. CT and MRI examination can estimate the resectability of the tumor; Ultrasound B can make sure its inside blood supply and the positional relationship between the mass and the surrounding vasculature. The diagnosis
of pPNETs is based primarily on histopathologic study and IHC, especially those with the characteristics of the Homer-Wright and neuroendocrine markers. Radical resection of the tumor is the most effective therapeutic method. The effect of adjuvant chemo-radiation is worth affirmation. Autologous stem cell rescue besides adjuvant chemotherapy has been associated with prolonged survival. |
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