Kui Li,Zhongyin Zhou,Ximing Xu,Hesheng Luo. Comparison of plastic and self-expandable metal stents in the palliative treatment of malignant biliary obstruction: a meta-analysis. Oncol Transl Med, 2014, 13: 375-378.
Comparison of plastic and self-expandable metal stents in the palliative treatment of malignant biliary obstruction: a meta-analysis
Received:June 14, 2014  Revised:August 01, 2014
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KeyWord:ERCP; stent placement; malignant biliary obstruction; meta-analysis
Author NameAffiliationE-mail
Kui Li Department of Gastroenterology, Renmin Hospital of Wuhan University guimuyu@foxmail.com 
Zhongyin Zhou Department of Gastroenterology, Renmin Hospital of Wuhan University zhouhu0425@163.com 
Ximing Xu Cancer Center, Renmin Hospital of Wuhan University  
Hesheng Luo Department of Gastroenterology, Renmin Hospital of Wuhan University  
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Abstract:
      Objective: Stent placement is one of the main methods in the palliative treatment of malignant biliary obstruction, including plastic and self-expandable metal stents. The comparison of stent patency between self-expandable metal and plastic stents in palliation of malignant biliary obstruction is meaningful. We carried out a meta-analysis to summarize current evidence for clinical efficacy of self-expandable metal and plastic stents in the treatment of malignant biliary obstruction. Methods: A comprehensive search of several databases including CNKI, WANFANG DATA, Sino MED. A fixed-effects or random-effects model was used to pool data of all study endpoint. Sensitivity analysis was also performed. Results: Eight randomized clinical trials were identified,including 633 patients. These results suggested that the self-expandable metal stents were associated with a significantly longer stent patency (OR=8.15; 95% CI: 2.80-23.76;I2=85%).No publication bias was observed. Conclusions: Self-expanding metal stents have a longer patency than plastic stents and offer adequate palliation in patients with malignant biliary obstruction.
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