Fei Gao,Lin Jia,Xiaobo Du,Yun Wang,Jianjun Han. Relationship between hepatitis B virus infection and hepatic metastasis in non-small cell lung cancer. Oncol Transl Med, 2014, 13: 212-214.
Relationship between hepatitis B virus infection and hepatic metastasis in non-small cell lung cancer
  
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KeyWord:hepatitis B virus (HBV); non-small cell lung cancer (NSCLC); hepatic metastasis
Author NameAffiliation
Fei Gao Department of Oncology, The Third Hospital of Mianyang, Mianyang 621000, China 
Lin Jia Department of Oncology, The Third Hospital of Mianyang, Mianyang 621001, China 
Xiaobo Du Department of Oncology, The Central Hospital of Mianyang, Mianyang 621600, China 
Yun Wang Department of Oncology, The Third Hospital of Mianyang, Mianyang 621003, China 
Jianjun Han Department of Oncology, The Third Hospital of Mianyang, Mianyang 621004, China 
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Abstract:
      Objective: The purpose of the study was to explore the relationship between hepatitis B virus (HBV) infection and hepatic metastasis in non-small cell lung cancer (NSCLC). Methods: Four hundred and eighty cases of NSCLC were retrospectively analyzed from January 2003 to January 2010, and the prevalence of hepatic metastasis of NSCLC in patients with and without hepatitis B virus infection were compared. Results: In the HBV carriers’ group, the prevalence of synchronous hepatic metastasis and metachronous hepatic metastasis were 13.2% and 5.9%, respectively. Meanwhile in the non-HBV group, those were 21.6% and 9.5% respectively. A significant difference between the two groups was found (P < 0.05). Conclusion: The prevalence of synchronous hepatic metastasis and metachronous hepatic  metastasis in non-small cell lung cancer with HBV infection are lower than those in non-HBV infection group. Hepatic metastasis is infrequent in HBV infected cases of NSCLC.
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